SCHEMBL2855099

SCHEMBL2855099

C=CC(=O)C=Cc1ccccc1CCCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.53
THRA P10827 3/20 0.47
THRB P10828 3/20 0.47
PTGER3 P43115 4/20 0.42
PTGER2 P43116 4/20 0.42
PTGER4 P35408 3/20 0.42
IAPP P10997 1/20 0.40
NFE2L2 Q16236 2/20 0.40
NFKB1 P19838 2/20 0.40
JUN P05412 1/20 0.40
TFEB P19484 1/20 0.40
HSD11B1 P28845 1/20 0.39
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
TBXA2R P21731 1/20 0.37
PTGDR Q13258 1/20 0.37
LIPG Q9Y5X9 1/20 0.37
HDAC3 O15379 2/20 0.37
HDAC4 P56524 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9725168 0.83 LMNA (0.53) THRATHRBPTGER3PTGER2PTGER4
SCHEMBL1542126 0.83 PTGER3 (0.56) PTGER3PTGER2PTGER4NFKB1TBXA2R
SCHEMBL7530108 0.83 PTGER3 (0.56) PTGER3PTGER2PTGER4NFKB1TBXA2R
SCHEMBL8702148 0.83 PTGER3 (0.56) PTGER3PTGER2PTGER4NFKB1TBXA2R
SCHEMBL9788952 0.82 PTGER3 (0.43) THRATHRBPTGER3PTGER2PTGER4
Alcohol SCHEMBL17474327 0.81 PTGER3 (0.55) PTGER3PTGER2PTGER4NFKB1TBXA2R
SCHEMBL2989498 0.79 MAPT (0.52) PTGER3PTGER2PTGER4NFKB1CYP3A4
Acrylic Acid SCHEMBL3803158 0.79 THRA (0.49) THRATHRBPTGER3PTGER2PTGER4
SCHEMBL16339259 0.79 PTGER3 (0.55) PTGER3PTGER2PTGER4NFKB1TBXA2R
SCHEMBL16339260 0.79 PTGER3 (0.55) PTGER3PTGER2PTGER4NFKB1TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1182452-B1 Method for ultrasonic detection of air bubbles GAMBRO RENAL PRODUCTS INC (US) 2010-01-20 EP disclosed
EP-1182452-A2 Method and apparatus for ultrasonic detection of air bubbles Gambro, Inc. (US) 2002-02-27 EP disclosed
EP-0643301-B1 Method and apparatus for ultrasonic detection of air bubbles GAMBRO INC (US) 2002-01-30 EP disclosed
EP-0643301-A1 Method and apparatus for ultrasonic detection of air bubbles COBE LABORATORIES, INC. (US) 1995-03-15 EP disclosed
US-5394732-A Method and apparatus for ultrasonic detection of air bubbles COBE LABORATORIES, INC. (US) 1995-03-07 US disclosed
EP-0392377-B1 Method and device for the separation of plasma or serum from whole blood ABBOTT LAB (US) 1995-02-15 EP disclosed
US-5064541-A MATRIX OF SINTERED POROUS MATERIAL WITH HYDROPHILIC SURFACE TO COLLECT A PREDETERMINED SAMPLE FOR ANALYSIS; CLINICAL DIAGNOSIS ABBOTT LABORATORIES (US) 1991-11-12 US disclosed
EP-0205145-B1 REACTIVE COEXTRUSION OF FUNCTIONALIZED POLYMERS AND PRODUCT THE DOW CHEMICAL COMPANY (US) 1991-05-02 EP disclosed
EP-0392377-A2 Method and device for the separation of plasma or serum from whole blood ABBOTT LABORATORIES (US) 1990-10-17 EP disclosed
US-4661303-A LAMINATION COVALENTLY BONDED THROUGH INTERACTION OF CYCLIC IMINO ETHER GROUPS AND COREACTIVE GROUP THE DOW CHEMICAL COMPANY (US) 1987-04-28 US disclosed
EP-0205145-A2 Reactive coextrusion of functionalized polymers and product THE DOW CHEMICAL COMPANY (US) 1986-12-17 EP disclosed
US-4013992-A DIVER'S PIEZOELECTRIC MICROPHONE WITH INTEGRAL AGC PREAMPLIFIER THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1977-03-22 US disclosed