Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.50 |
| ▸ | IKBKB | O14920 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 3/20 | 0.44 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | IDH2 | P48735 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6464494 | 0.78 | CTSK (0.41) | IKBKBHRH4CDK1CDK4CCNB1 | |
| SCHEMBL6463619 | 0.77 | PAK4 (0.50) | MKNK2HRH4CDK1CDK4CCNB1 | |
| SCHEMBL6461912 | 0.77 | JAK3 (0.41) | IKBKBHRH4CDK1CDK4CCNB1 | |
| SCHEMBL6457779 | 0.77 | PAK4 (0.50) | MKNK2HRH4CDK1CDK4CCNB1 | |
| SCHEMBL13779899 | 0.76 | IKBKB (0.57) | IKBKBHRH4BRD4ATAD2CDK1 | |
| Hydrochloric Acid SCHEMBL6464145 | 0.76 | PAK4 (0.49) | MKNK2HRH4CDK1CDK4CCNB1 | |
| SCHEMBL17961781 | 0.75 | KDM4E (0.55) | MKNK1MKNK2IKBKBHRH3HRH4 | |
| SCHEMBL17961784 | 0.75 | KDM4E (0.55) | MKNK1MKNK2IKBKBHRH3HRH4 | |
| SCHEMBL17961788 | 0.75 | KDM4E (0.55) | MKNK1MKNK2IKBKBHRH3HRH4 | |
| SCHEMBL12526259 | 0.75 | IDH2 (0.50) | MKNK1MKNK2IKBKBHRH3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638373-A | Cyclin-dependent kinase inhibitors | 金耐特生物制药公司 | 2021-04-09 | — | — | CN | disclosed |