Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 2/20 | 0.53 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 6/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | BTK | Q06187 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FPR3 | P25089 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 2/20 | 0.46 |
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23292461 | 1.00 | CCNK (0.53) | CCNKCDK12USP30PIK3CDALDH1A1 | |
| SCHEMBL889080 | 1.00 | CCNK (0.53) | CCNKCDK12USP30PIK3CDALDH1A1 | |
| SCHEMBL269894 | 0.93 | FPR2 (0.48) | CCNKCDK12USP30PIK3CDBTK | |
| SCHEMBL269817 | 0.93 | FPR2 (0.48) | CCNKCDK12USP30PIK3CDBTK | |
| SCHEMBL3774389 | 0.93 | ALDH1A1 (0.55) | CCNKCDK12USP30ALDH1A1NPC1 | |
| SCHEMBL29161251 | 0.90 | CCNK (0.44) | CCNKCDK12USP30ALDH1A1NPC1 | |
| SCHEMBL28549570 | 0.89 | USP30 (0.53) | CCNKCDK12USP30PIK3CDALDH1A1 | |
| SCHEMBL22895509 | 0.89 | USP30 (0.53) | CCNKCDK12USP30PIK3CDALDH1A1 | |
| SCHEMBL23292240 | 0.89 | USP30 (0.53) | CCNKCDK12USP30PIK3CDALDH1A1 | |
| SCHEMBL22895519 | 0.88 | CCNK (0.53) | CCNKCDK12USP30PIK3CDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638373-A | Cyclin-dependent kinase inhibitors | 金耐特生物制药公司 | 2021-04-09 | — | — | CN | disclosed |