SCHEMBL28552004

SCHEMBL28552004

CCCc1ccc(C(=O)OCC)c(C(=O)OC(=O)c2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.46
CYP4F2 P78329 2/20 0.44
CYP4A11 Q02928 2/20 0.44
LMNA P02545 1/20 0.43
NPC1 O15118 1/20 0.42
GAA P10253 1/20 0.42
RAB9A P51151 1/20 0.42
ALDH1A1 P00352 2/20 0.41
HSD17B10 Q99714 1/20 0.41
MAPT P10636 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
METAP2 P50579 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28549196 0.93 CYP4F2 (0.48) TSHRSMN1; SMN2CYP4F2CYP4A11LMNA
SCHEMBL28547104 0.91 TSHR (0.54) TSHRSMN1; SMN2CYP4F2CYP4A11LMNA
SCHEMBL28911430 0.84 TSHR (0.47) TSHRSMN1; SMN2CYP4F2CYP4A11LMNA
SCHEMBL28549081 0.84 TSHR (0.47) TSHRSMN1; SMN2CYP4F2CYP4A11LMNA
SCHEMBL28552669 0.84 TSHR (0.56) TSHRSMN1; SMN2LMNANPC1GAA
SCHEMBL28543775 0.83 TSHR (0.72) TSHRSMN1; SMN2LMNANPC1GAA
SCHEMBL28553544 0.83 LMNA (0.59) TSHRLMNANPC1ALDH1A1HSD17B10
SCHEMBL28548521 0.82 TSHR (0.45) TSHRSMN1; SMN2CYP4F2CYP4A11LMNA
SCHEMBL28549080 0.81 CYP4F2 (0.44) TSHRSMN1; SMN2CYP4F2CYP4A11LMNA
SCHEMBL28685023 0.79 LMNA (0.53) TSHRSMN1; SMN2LMNANPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553706-B Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553703-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553711-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553706-B Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553703-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553711-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed