SCHEMBL28552008

SCHEMBL28552008

CCC(=O)OC(=O)c1ccccc1OC(=O)c1ccccc1CC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.49
HSD17B10 Q99714 4/20 0.49
LMNA P02545 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
SLC6A3 Q01959 1/20 0.45
PTGS2 P35354 2/20 0.44
ALDH1A1 P00352 3/20 0.43
HPGD P15428 2/20 0.43
KMT2A Q03164 7/20 0.43
MEN1 O00255 1/20 0.42
RECQL P46063 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
TSHR P16473 3/20 0.40
ESR1 P03372 2/20 0.40
HTT P42858 1/20 0.40
ESR2 Q92731 1/20 0.40
MAPT P10636 1/20 0.40
ITGB3 P05106 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27770565 0.89 TSHR (0.47) HSD17B10LMNAALDH1A1KMT2ATSHR
SCHEMBL28537032 0.88 HSD17B10 (0.56) KDM4EHSD17B10LMNACYP1A2CYP2C9
SCHEMBL6787728 0.85 KDM4E (0.51) KDM4EHSD17B10LMNACYP1A2CYP2C9
SCHEMBL28549086 0.85 SLC6A3 (0.57) KDM4EHSD17B10LMNACYP1A2CYP2C9
SCHEMBL28537035 0.81 TSHR (0.43) HSD17B10LMNAALDH1A1TSHRHTT
SCHEMBL739158 0.80 TSHR (0.52) HSD17B10LMNAALDH1A1KMT2ATSHR
SCHEMBL16672925 0.80 NPC1 (0.50) KDM4EHSD17B10LMNACYP1A2CYP2C9
SCHEMBL27875398 0.79 CTSD (0.54) HSD17B10LMNAALDH1A1HPGDKMT2A
SCHEMBL5157613 0.79 TSHR (0.52) KDM4EHSD17B10LMNACYP1A2CYP2C9
SCHEMBL16672527 0.78 MAPT (0.56) KDM4EHSD17B10LMNACYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553703-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553706-B Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553711-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553703-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553706-B Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553711-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed