Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.47 |
| ▸ | THRA | P10827 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28548442 | 0.98 | ALDH1A1 (0.54) | ALDH1A1HPGDHSD17B10GPR84THRA | |
| SCHEMBL16050400 | 0.98 | ALDH1A1 (0.57) | ALDH1A1HPGDHSD17B10GPR84THRA | |
| SCHEMBL16050565 | 0.97 | ALDH1A1 (0.56) | ALDH1A1HPGDHSD17B10GPR84THRA | |
| SCHEMBL20978824 | 0.97 | ALDH1A1 (0.56) | ALDH1A1HPGDHSD17B10GPR84THRA | |
| SCHEMBL17672771 | 0.89 | ALDH1A1 (0.54) | ALDH1A1HPGDHSD17B10GPR84THRA | |
| SCHEMBL17678267 | 0.86 | GPR84 (0.50) | ALDH1A1GPR84TSHRRARBPPARA | |
| SCHEMBL28538520 | 0.85 | ALDH1A1 (0.57) | ALDH1A1HPGDHSD17B10GPR84THRA | |
| SCHEMBL19166902 | 0.85 | GPR84 (0.49) | ALDH1A1GPR84THRATHRBTSHR | |
| SCHEMBL17678266 | 0.84 | GPR84 (0.49) | ALDH1A1GPR84TSHRRARBPPARG | |
| SCHEMBL19166233 | 0.84 | GPR84 (0.47) | ALDH1A1GPR84THRATHRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106999458-B | Substituted aromatic compounds and pharmaceutical compositions for the prevention and treatment of diabetes | 普罗米蒂克医药SMT有限公司 | 2021-04-13 | — | — | CN | disclosed |