Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.61 |
| ▸ | GSR | P00390 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.43 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28553382 | 0.83 | SRC (0.45) | SRCGSRTHRBPOLBKMT2A | |
| Mandelic Acid SCHEMBL21383946 | 0.82 | GSR (0.62) | GSRTHRBPOLBKMT2ATDP1 | |
| Aminodiphenylmethane SCHEMBL14167635 | 0.82 | GSR (0.67) | GSRTHRBPOLBKMT2ATDP1 | |
| Aminodiphenylmethane SCHEMBL23925166 | 0.82 | GSR (0.67) | GSRTHRBPOLBKMT2ATDP1 | |
| Lysine SCHEMBL16553019 | 0.81 | GSR (0.61) | GSRTHRBPOLBKMT2ATDP1 | |
| Lysine SCHEMBL16553020 | 0.81 | GSR (0.61) | GSRTHRBPOLBKMT2ATDP1 | |
| Diphenylacetic Acid SCHEMBL10358556 | 0.81 | GSR (0.65) | GSRTHRBPOLBKMT2ATDP1 | |
| Phenylglycine SCHEMBL23629659 | 0.81 | GSR (0.65) | GSRTHRBPOLBKMT2ATDP1 | |
| Anthraquinone SCHEMBL8876801 | 0.79 | GSR (0.67) | GSRTHRBPOLBKMT2ATDP1 | |
| Lysine SCHEMBL29438093 | 0.78 | GSR (0.61) | GSRTHRBPOLBKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108373475-B | Preparation method of sulbenicillin sodium | 山东四环药业股份有限公司 | 2020-12-01 | — | — | CN | disclosed |