Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31229951 | 0.85 | NPC1 (0.47) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL152733 | 0.80 | NUDT1 (0.49) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL179869 | 0.79 | NPC1 (0.44) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL2321138 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL6175391 | 0.79 | NUDT1 (0.48) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| Bromide SCHEMBL29572453 | 0.79 | NUDT1 (0.48) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL29571385 | 0.79 | NUDT1 (0.48) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL1150474 | 0.78 | NPC1 (0.43) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL20267553 | 0.77 | ALDH1A1 (0.44) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL262815 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107636009-B | Glucagon derivatives with improved stability | 韩美药品株式会社 | 2021-04-16 | — | — | CN | disclosed |