SCHEMBL28554338

SCHEMBL28554338

CCCCCCCCCCCCCCCCCCOc1ccccc1C(=O)Cl

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.72
CYP3A4 P08684 2/20 0.72
MAPT P10636 2/20 0.72
MEN1 O00255 1/20 0.72
NR1I2 O75469 1/20 0.72
CHRM2 P08172 1/20 0.72
ADRA2A P08913 1/20 0.72
OPRK1 P41145 1/20 0.72
HTR2B P41595 1/20 0.72
SLC6A3 Q01959 1/20 0.72
KMT2A Q03164 1/20 0.72
HDAC6 Q9UBN7 1/20 0.72
ALDH1A1 P00352 4/20 0.57
TSHR P16473 2/20 0.57
NPSR1 Q6W5P4 1/20 0.57
PTPN11 Q06124 2/20 0.56
CNR1 P21554 3/20 0.55
CNR2 P34972 3/20 0.55
FAAH O00519 1/20 0.55
TP53 P04637 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1983637 1.00 LMNA (0.72) LMNACYP3A4MAPTMEN1NR1I2
SCHEMBL8982634 1.00 LMNA (0.72) LMNACYP3A4MAPTMEN1NR1I2
SCHEMBL1045431 1.00 LMNA (0.72) LMNACYP3A4MAPTMEN1NR1I2
SCHEMBL6112609 1.00 LMNA (0.72) LMNACYP3A4MAPTMEN1NR1I2
SCHEMBL10506979 1.00 LMNA (0.72) LMNACYP3A4MAPTMEN1NR1I2
SCHEMBL8982612 1.00 LMNA (0.72) LMNACYP3A4MAPTMEN1NR1I2
SCHEMBL9626775 1.00 LMNA (0.72) LMNACYP3A4MAPTMEN1NR1I2
SCHEMBL7366543 0.98 LMNA (0.69) LMNACYP3A4MAPTMEN1NR1I2
SCHEMBL5827955 0.93 LMNA (0.62) LMNACYP3A4MAPTMEN1NR1I2
SCHEMBL8924404 0.92 LMNA (0.58) LMNACYP3A4MAPTMEN1NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106795186-B Process for preparing morpholino oligonucleotides 味之素株式会社 2021-03-02 CN disclosed