SCHEMBL7366543

SCHEMBL7366543

CCCCCOc1ccccc1C(=O)Cl

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.69
CYP3A4 P08684 2/20 0.69
MAPT P10636 2/20 0.69
MEN1 O00255 2/20 0.69
KMT2A Q03164 2/20 0.69
NR1I2 O75469 1/20 0.69
CHRM2 P08172 1/20 0.69
ADRA2A P08913 1/20 0.69
OPRK1 P41145 1/20 0.69
HTR2B P41595 1/20 0.69
SLC6A3 Q01959 1/20 0.69
HDAC6 Q9UBN7 1/20 0.69
NPSR1 Q6W5P4 1/20 0.58
CNR1 P21554 3/20 0.56
CNR2 P34972 3/20 0.56
FAAH O00519 1/20 0.56
TSHR P16473 4/20 0.56
TP53 P04637 1/20 0.56
MAPK1 P28482 1/20 0.56
ALDH1A1 P00352 4/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9626775 0.98 LMNA (0.72) LMNACYP3A4MAPTMEN1KMT2A
SCHEMBL1045431 0.98 LMNA (0.72) LMNACYP3A4MAPTMEN1KMT2A
SCHEMBL10506979 0.98 LMNA (0.72) LMNACYP3A4MAPTMEN1KMT2A
SCHEMBL28554338 0.98 LMNA (0.72) LMNACYP3A4MAPTMEN1KMT2A
SCHEMBL1983637 0.98 LMNA (0.72) LMNACYP3A4MAPTMEN1KMT2A
SCHEMBL8982612 0.98 LMNA (0.72) LMNACYP3A4MAPTMEN1KMT2A
SCHEMBL8982634 0.98 LMNA (0.72) LMNACYP3A4MAPTMEN1KMT2A
SCHEMBL6112609 0.98 LMNA (0.72) LMNACYP3A4MAPTMEN1KMT2A
SCHEMBL5827955 0.95 LMNA (0.62) LMNACYP3A4MAPTMEN1KMT2A
SCHEMBL28435821 0.90 LMNA (0.57) LMNACYP3A4MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104725226-A Preparation method of phenone DSM IP ASSETS BV 2015-06-24 CN disclosed
CN-102341362-B Method for preparing acylbenzenes DSM IP ASSETS BV 2015-03-11 CN disclosed
CN-102199293-A Liquid-crystalline polysiloxane type [beta]-crystalline polypropylene nucleating agent, and preparation method thereof UNIV NORTHEASTERN 2011-09-28 CN disclosed
CN-1106380-C New synthetic catechol derivatives, method for production and use thereof GRILENTHAL GMBH (DE) 2003-04-23 CN disclosed
CN-1075064-C New benzoxazinedione derivatives, method of producing them and use thereof GRUENENTHAL GMBH (DE) 2001-11-21 CN disclosed
EP-0907633-B1 NEW SYNTHETIC CATECHOL DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF GRUENENTHAL GMBH (DE) 2001-08-22 EP disclosed
US-6013647-A BACTERICIDES GRUENENTHAL GMBH (DE) 2000-01-11 US disclosed
EP-0941236-A1 CYCLOHEXAPEPTIDES HAVING ANTIMICROBIAL ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-09-15 EP disclosed
CN-1222905-A New synthetic catechol derivatives, method for production and use thereof GRILENTHAL GMBH (DE) 1999-07-14 CN disclosed
EP-0907633-A1 NEW SYNTHETIC CATECHOL DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF Grünenthal GmbH (DE) 1999-04-14 EP disclosed
CN-1195664-A New benzoxazinedione derivatives, method of producing them and use thereof GRUENENTHAL GMBH (DE) 1998-10-14 CN disclosed
WO-1998023637-A1 CYCLOHEXAPEPTIDES HAVING ANTIMICROBIAL ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-06-04 WO disclosed
WO-1997049670-A1 NEW SYNTHETIC CATECHOL DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF Grünenthal GmbH (DE) 1997-12-31 WO disclosed
US-4744818-A Herbicidal N-halo-5(substituted-phenoxy or -pyridyloxy)-2-substituted benzoic acid sulfonamides and sulfamates RHONE-POULENC AGROCHIMIE (FR) 1988-05-17 US disclosed
US-4287174-A CONTAINING A QUATERNARY AMMONIUM CARBOXY ZWITTERIONIC COMPOUND AND AN ANTACID THE PROCTOR & GAMBLE COMPANY (US) 1981-09-01 US disclosed
US-4276430-A FOR TOPICAL APPLICATION AND SYSTEMIC ADMINISTRATION; ESTERS OF DIHYDROXYBENZOIC ACID THE PROCTER & GAMBLE COMPANY (US) 1981-06-30 US disclosed
US-4275059-A IN COMBINATION WITH A DIPHOSPHONATE COMPOUND THE PROCTER & GAMBLE COMPANY (US) 1981-06-23 US disclosed
US-4199576-A DERIVATIVES OF SALICYCLIC ACID THE PROCTER & GAMBLE COMPANY (US) 1980-04-22 US disclosed
EP-0004686-A2 Anti-ulcer composition THE PROCTER & GAMBLE COMPANY (US) 1979-10-17 EP disclosed