Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRAP1 | Q12931 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 7/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28548817 | 0.85 | TRAP1 (0.35) | TRAP1CHRNA7HIF1A | |
| Bromide SCHEMBL23387051 | 0.83 | CHRNA7 (0.36) | TRAP1CHRNA7HIF1A | |
| SCHEMBL28543392 | 0.75 | — | — | |
| Bromide SCHEMBL10826278 | 0.75 | ALDH1A1 (0.40) | TRAP1CHRNA7HIF1A | |
| Bromide SCHEMBL29019373 | 0.70 | TRAP1 (0.33) | TRAP1CHRNA7HIF1A | |
| SCHEMBL28548314 | 0.69 | — | — | |
| Bromide SCHEMBL23387085 | 0.69 | CHRNA7 (0.34) | TRAP1CHRNA7HIF1A | |
| Bromide SCHEMBL7332724 | 0.69 | MEN1 (0.36) | — | |
| Iodide SCHEMBL11476441 | 0.68 | HIF1A (0.34) | TRAP1CHRNA7HIF1A | |
| Bromide SCHEMBL10375203 | 0.68 | HIF1A (0.54) | TRAP1CHRNA7HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638868-A | Fatty acid derivatives labelled with positron-emitting radionuclides | 安斯泰来制药株式会社 | 2021-04-09 | — | — | CN | disclosed |