SCHEMBL28554347

SCHEMBL28554347

CCCC(CCCC/C=C\CCCCSCCC(=O)OC)OC1COCCO1

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HKDC1 Q2TB90 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
SAE1 Q9UBE0 1/20 0.36
UBA2 Q9UBT2 1/20 0.36
EPHX2 P34913 2/20 0.33
PTGER4 P35408 2/20 0.33
PTGER3 P43115 2/20 0.33
ALOX5 P09917 1/20 0.33
PTGER2 P43116 1/20 0.32
TBXA2R P21731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29019368 0.88 KDM4E (0.35) KDM4EALDH1A1HKDC1TDP1SAE1
SCHEMBL23387063 0.87 KDM4E (0.34) KDM4EALDH1A1HKDC1TDP1SAE1
SCHEMBL28547059 0.87 KDM4E (0.33) KDM4EALDH1A1HKDC1TDP1SAE1
SCHEMBL28548313 0.79
SCHEMBL28538714 0.75
SCHEMBL29019365 0.74 EPHX2 (0.33) KDM4EALDH1A1HKDC1TDP1SAE1
SCHEMBL23387082 0.73 L3MBTL1 (0.43) KDM4EALDH1A1HKDC1TDP1SAE1
SCHEMBL23387068 0.73 EPHX2 (0.32) KDM4EALDH1A1HKDC1TDP1SAE1
SCHEMBL23387069 0.69 ALDH1A1 (0.43) ALDH1A1EPHX2ALOX5
SCHEMBL28550818 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112638868-A Fatty acid derivatives labelled with positron-emitting radionuclides 安斯泰来制药株式会社 2021-04-09 CN disclosed