Ethyl Cinnamate

Ethyl Cinnamate

SCHEMBL28554384

CC(C)c1ccc(/C=C/C(=O)O)cc1.CCOC(=O)/C=C/c1ccccc1

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.66
MAPK1 P28482 1/20 0.66
CA12 O43570 2/20 0.57
CA7 P43166 2/20 0.57
CA9 Q16790 2/20 0.57
CA14 Q9ULX7 2/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
EGFR P00533 1/20 0.51
CYP3A4 P08684 1/20 0.51
LMNA P02545 3/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
ALDH1A1 P00352 2/20 0.50
TTR P02766 1/20 0.50
DPP4 P27487 1/20 0.50
PTGS2 P35354 1/20 0.50
HDAC3 O15379 1/20 0.50
TNKS O95271 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Cinnamate SCHEMBL28554385 1.00 KDM4E (0.66) KDM4EMAPK1CA12CA7CA9
Ethyl 3-(4-Isopropylphenyl)Acrylate SCHEMBL156247 0.90 CA12 (0.69) KDM4EMAPK1CA12CA7CA9
Ethyl 3-(4-Isopropylphenyl)Acrylate SCHEMBL526299 0.90 CA12 (0.69) KDM4EMAPK1CA12CA7CA9
Ethyl Cinnamate SCHEMBL29527453 0.89 CA12 (0.66) KDM4ECA12CA7CA9CA14
Ethyl 3-(4-Isopropylphenyl)Acrylate SCHEMBL28182168 0.88 PTGS2 (0.61) KDM4EMAPK1CA12CA7CA9
Ethyl 3-(4-Isopropylphenyl)Acrylate SCHEMBL28182167 0.88 PTGS2 (0.61) KDM4EMAPK1CA12CA7CA9
Ethyl Cinnamate SCHEMBL28948991 0.86 KDM4E (0.48) KDM4EMAPK1CA12CA7CA9
Ethyl Cinnamate SCHEMBL28948990 0.86 KDM4E (0.48) KDM4EMAPK1CA12CA7CA9
SCHEMBL1579390 0.86 CA12 (0.75) KDM4EMAPK1CA12CA7CA9
SCHEMBL1579391 0.86 CA12 (0.75) KDM4EMAPK1CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112638355-A Cosmetic and cleaning product 株式会社资生堂 2021-04-09 CN disclosed