Ethyl Cinnamate

Ethyl Cinnamate

SCHEMBL28948990

CC(C)c1ccc(/C=C/C(=O)O)c(C(C)C)c1.CCOC(=O)/C=C/c1ccccc1

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.48
MAPK1 P28482 1/20 0.48
LMNA P02545 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PTGS2 P35354 1/20 0.46
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
ALDH1A1 P00352 3/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CYP3A4 P08684 1/20 0.44
TTR P02766 1/20 0.43
DPP4 P27487 1/20 0.43
ESR1 P03372 1/20 0.42
TYR P14679 1/20 0.42
GAA P10253 1/20 0.42
NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Cinnamate SCHEMBL28948991 1.00 KDM4E (0.48) KDM4EMAPK1LMNAL3MBTL1PTGS2
SCHEMBL15514 0.89 TYR (0.50) LMNACA12CA1CA2CA7
SCHEMBL648606 0.89 TYR (0.50) LMNACA12CA1CA2CA7
E-Methyl Cinnamate SCHEMBL28948986 0.88 KDM4E (0.51) KDM4EMAPK1LMNAL3MBTL1CA12
E-Methyl Cinnamate SCHEMBL28810582 0.88 KDM4E (0.51) KDM4EMAPK1LMNAL3MBTL1CA12
Ethyl Cinnamate SCHEMBL28554385 0.86 KDM4E (0.66) KDM4EMAPK1LMNAL3MBTL1PTGS2
Ethyl Cinnamate SCHEMBL28554384 0.86 KDM4E (0.66) KDM4EMAPK1LMNAL3MBTL1PTGS2
Isopropyl 3-(4-Isopropylphenyl)Acrylate SCHEMBL28558517 0.85 CA12 (0.48) KDM4EMAPK1LMNACA12CA1
E-Methyl Cinnamate SCHEMBL28948979 0.81 KDM4E (0.51) KDM4EMAPK1LMNAL3MBTL1CA12
E-Methyl Cinnamate SCHEMBL28948981 0.81 KDM4E (0.51) KDM4EMAPK1LMNAL3MBTL1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115531248-A Oil-in-water type emulsified solid cosmetic 株式会社资生堂 2022-12-30 CN disclosed