Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25072433 | 0.89 | KDM4E (0.46) | KDM4ENR4A2TSHRBRD4DAPK3 | |
| SCHEMBL7853670 | 0.87 | NOTUM (0.37) | KDM4ENR4A2TSHRLMNAHSD17B10 | |
| SCHEMBL2781478 | 0.82 | NOTUM (0.41) | KDM4EHSD17B10HPGDNOTUMHTT | |
| SCHEMBL9723823 | 0.80 | NOTUM (0.40) | KDM4EHSD17B10HPGDNOTUMHTT | |
| Ethane SCHEMBL15559374 | 0.79 | ABL1 (0.38) | KDM4ETSHRPABPC1EIF4HDAPK3 | |
| SCHEMBL9826739 | 0.77 | KDM4E (0.46) | KDM4ENR4A2TSHRBRD4DAPK3 | |
| SCHEMBL11286998 | 0.77 | KDM4E (0.46) | KDM4ENR4A2TSHRBRD4PABPC1 | |
| SCHEMBL10940902 | 0.76 | NR4A2 (0.43) | KDM4ENR4A2BRD4HPGDALDH1A1 | |
| SCHEMBL17700936 | 0.76 | KDM4E (0.45) | KDM4ENR4A2TSHRBRD4PABPC1 | |
| SCHEMBL22362939 | 0.76 | KDM4E (0.45) | KDM4ENR4A2TSHRBRD4PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112661688-B | Synthetic method of non-steroidal anti-inflammatory drug tolmetin | 杭州迪克科技有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-112661688-A | Synthetic method of non-steroidal anti-inflammatory drug tolmetin | 杭州迪克科技有限公司 | 2021-04-16 | — | — | CN | disclosed |