Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | HAAO | P46952 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2781478 | 0.89 | NOTUM (0.41) | NOTUMPTPN1ALDH1A1ALOX15CYP1A2 | |
| SCHEMBL9635530 | 0.87 | ALDH1A1 (0.50) | PTPN1ALDH1A1ALOX15KMT2APOLB | |
| SCHEMBL31342301 | 0.87 | AKR1C3 (0.50) | NOTUMALDH1A1ALOX15POLBAKR1C3 | |
| SCHEMBL7853670 | 0.82 | NOTUM (0.37) | NOTUMPTPN1ALDH1A1ALOX15CYP1A2 | |
| SCHEMBL28554392 | 0.80 | KDM4E (0.44) | NOTUMALDH1A1ALOX15KMT2AMEN1 | |
| SCHEMBL4562515 | 0.76 | NOTUM (0.55) | NOTUMALDH1A1ALOX15CYP1A2KMT2A | |
| SCHEMBL5493295 | 0.76 | NOTUM (0.41) | NOTUMPTPN1ALDH1A1ALOX15CYP1A2 | |
| SCHEMBL10940971 | 0.75 | ACMSD (0.42) | NOTUMPTPN1ALDH1A1CYP1A2KMT2A | |
| Hydrochloric Acid SCHEMBL30678145 | 0.74 | NOTUM (0.53) | NOTUMALDH1A1ALOX15CYP1A2KMT2A | |
| SCHEMBL5173280 | 0.74 | GABRP (0.42) | NOTUMPTPN1ALDH1A1ALOX15CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164470-A | Polymer compositions | SHELL OIL COMPANY (US) | 1992-11-17 | — | — | US | disclosed |