O-Xylene

O-Xylene

SCHEMBL28554571

CCCCN=C=O.Cc1ccccc1C

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 2/20 0.40
NFE2L2 Q16236 2/20 0.40
TSHR P16473 1/20 0.39
ACHE P22303 1/20 0.39
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
P2RX7 Q99572 1/20 0.34
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
NAAA Q02083 1/20 0.32
CTBP2 P56545 1/20 0.32
MIF P14174 1/20 0.32
CNR2 P34972 1/20 0.32
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL11490623 0.86 TSHR (0.48) KEAP1NFE2L2TSHRACHEKMT2A
Benzene SCHEMBL11855931 0.83 NAAA (0.39) MEN1KMT2ANPSR1GABRA1GABRB2
Benzene SCHEMBL28876662 0.83 NAAA (0.39) MEN1KMT2ANPSR1GABRA1GABRB2
SCHEMBL9919 0.81
O-Xylene SCHEMBL27972484 0.81 TSHR (0.39) KEAP1NFE2L2TSHRACHEP2RX7
Toluene SCHEMBL28100339 0.80 LMNA (0.38) KEAP1NFE2L2TSHRACHENAAA
SCHEMBL11419613 0.80 MIF (0.56) NAAAMIFCNR2
Benzoic Acid SCHEMBL1793582 0.79 TSHR (0.47) TSHRALDH1A1TP53NAAA
Hydrochloric Acid SCHEMBL8196526 0.79
Fluoride SCHEMBL28174258 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112552214-A Production process for improving quality of sulfonyl isocyanate 安徽广信农化股份有限公司 2021-03-26 CN claimed
CN-112552214-A Production process for improving quality of sulfonyl isocyanate 安徽广信农化股份有限公司 2021-03-26 CN disclosed