Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29687970 | 0.91 | POLB (0.67) | POLBSMN1; SMN2LMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5733527 | 0.84 | MAPT (0.61) | HTR2CALDH1A1USP2MAPT | |
| Morpholine SCHEMBL28546953 | 0.81 | LMNA (0.69) | POLBHTR2CSMN1; SMN2LMNAKMT2A | |
| SCHEMBL7267448 | 0.80 | POLB (0.63) | POLBSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL12793245 | 0.78 | POLB (0.88) | POLBSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL847277 | 0.77 | POLB (0.69) | POLBSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL4811982 | 0.77 | POLB (0.63) | POLBSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL18553718 | 0.77 | KDM4E (0.65) | POLBHTR2CSMN1; SMN2LMNAKMT2A | |
| SCHEMBL8726184 | 0.74 | POLB (0.73) | POLBSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL7262000 | 0.74 | MAPT (0.59) | HTR2CALDH1A1USP2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112679292-B | Synthesis method of secondary sulfonamide compound | 复旦大学 | 2022-05-20 | — | — | CN | disclosed |
| CN-112679292-A | Synthesis method of secondary sulfonamide compound | 复旦大学 | 2021-04-20 | — | — | CN | disclosed |