SCHEMBL28555437

SCHEMBL28555437

C[Si](C)(C)C#CC[C@@H](O)CCl

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15611822 1.00 CA1 (0.33) CA1CA2CA9ALDH1A1TSHR
SCHEMBL28555438 1.00 CA1 (0.33) CA1CA2CA9ALDH1A1TSHR
SCHEMBL26441527 0.79
SCHEMBL10314778 0.79
SCHEMBL16821017 0.79 LMNA (0.36) ALDH1A1
SCHEMBL16821014 0.79 LMNA (0.36) ALDH1A1
SCHEMBL16821062 0.79 LMNA (0.36) ALDH1A1
SCHEMBL10314776 0.79
SCHEMBL15786358 0.78 CA1 (0.31) CA1CA2CA9
SCHEMBL7145096 0.76 CA1 (0.32) CA1CA2CA9ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109776479-B Preparation method of medical intermediate 绍兴文理学院 2021-05-04 CN claimed
CN-109776479-B Preparation method of medical intermediate 绍兴文理学院 2021-05-04 CN disclosed