SCHEMBL28555688

SCHEMBL28555688

COc1cccc([C@@]2(O)CCN(C(=O)O)C[C@@H]2CN(C)C)c1

nearest known ligand 0.82

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 10/20 0.82
OPRK1 P41145 11/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28561605 1.00 OPRD1 (0.82) OPRD1OPRK1
SCHEMBL24969502 0.90 OPRD1 (1.00) OPRD1OPRK1
Hydrochloric Acid SCHEMBL30206657 0.89 OPRD1 (0.98) OPRD1OPRK1
SCHEMBL24970012 0.89 OPRK1 (0.84) OPRD1OPRK1
Hydrochloric Acid SCHEMBL28583489 0.89 OPRK1 (0.82) OPRD1OPRK1
SCHEMBL24970002 0.89 OPRK1 (0.77) OPRD1OPRK1
SCHEMBL24969507 0.89 OPRK1 (1.00) OPRD1OPRK1
SCHEMBL24969512 0.89 OPRD1 (1.00) OPRD1OPRK1
SCHEMBL24969221 0.88 OPRD1 (0.73) OPRD1OPRK1
SCHEMBL24969197 0.88 OPRD1 (0.73) OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112759544-B Preparation method and pharmaceutical application of 3- (dimethylaminomethyl) piperidine-4-alcohol derivative 复旦大学 2022-08-26 CN disclosed
CN-112759544-A Preparation method and pharmaceutical application of 3- (dimethylaminomethyl) piperidine-4-alcohol derivative 复旦大学 2021-05-07 CN disclosed