Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.36 |
| ▸ | USP2 | O75604 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30231201 | 1.00 | ALOX5 (0.43) | ALOX5MEN1KMT2AHCRTR1ALDH1A1 | |
| SCHEMBL19231294 | 0.86 | CYP11B1 (0.44) | ALOX5MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL30868890 | 0.81 | FGFR1 (0.46) | ALOX5MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL19200298 | 0.81 | FGFR1 (0.46) | ALOX5MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL28521583 | 0.79 | HPGD (0.46) | KMT2AHCRTR1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9372735 | 0.79 | ALDH1A1 (0.37) | ALOX5MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL30231132 | 0.79 | HPGD (0.46) | KMT2AHCRTR1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL22655273 | 0.79 | ALDH1A1 (0.43) | ALOX5MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL30231161 | 0.79 | NPSR1 (0.43) | ALOX5MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL28921458 | 0.79 | NPSR1 (0.43) | ALOX5MEN1KMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118406016-A | Synthesis method and application of bicyclo [1, 1] pentane difunctional derivative | 天津科技大学 | 2024-07-30 | — | — | CN | disclosed |
| CN-114524773-B | Synthesis method of aryl quinoxaline compound promoted by mechanical force | 浙江工业大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-114920706-B | Method for preparing 3-acyl-quinoxaline-2 (1H) -ketone by ball milling method | 新乡市润宇新材料科技有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-116789610-A | Photocatalytic preparation method of quinoxaline-2, 3-diketone compound | 湖南科技学院 | 2023-09-22 | — | — | CN | disclosed |
| CN-116410147-A | Method for rapidly preparing 3-acyl-quinoxaline-2 (1H) -ketone under ball milling condition | 新乡市润宇新材料科技有限公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-114524805-B | Application of solid acid catalysis multi-component reaction in preparation of fluorine-containing medicine | 浙江树人学院（浙江树人大学） | 2023-01-24 | — | — | CN | disclosed |
| CN-115385863-A | Synthetic method of 3- (diethoxymethyl) -1-alkyl-2 (1H) -quinoxalinone derivative | 河南师范大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-114920706-A | Method for preparing 3-acyl-quinoxaline-2 (1H) -ketone by ball milling method | 新乡市润宇新材料科技有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-113264923-B | Synthesis method of 3-gamma-lactam/acylamino alkyl substituted quinoxalinone derivative | 浙江工业大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-110483421-B | Preparation method of quinoxalinone derivative | 沈阳师范大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-114524805-A | Application of solid acid catalysis multi-component reaction in preparation of fluorine-containing medicine | 浙江树人学院（浙江树人大学） | 2022-05-24 | — | — | CN | disclosed |
| CN-114524773-A | Method for synthesizing aryl quinoxaline compound promoted by mechanical force | 浙江工业大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-110437164-B | Method for synthesizing C-3 alkyl substituted quinoxalinone derivative based on Minisci reaction | 浙江工业大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-113264923-A | Synthesis method of 3-gamma-lactam/acylamino alkyl substituted quinoxalinone derivative | 浙江工业大学 | 2021-08-17 | — | — | CN | disclosed |
| CN-108752325-B | Preparation method of 3-oxyalkyl quinoxaline-2 (1H) -ketone compound | 曲阜师范大学 | 2021-03-23 | — | — | CN | disclosed |