Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | KHK | P50053 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27167661 | 0.75 | DDB1 (0.36) | KHK | |
| SCHEMBL26636968 | 0.73 | CRBN (0.64) | — | |
| SCHEMBL29976664 | 0.73 | DDB1 (0.62) | — | |
| SCHEMBL26637434 | 0.73 | CRBN (0.64) | — | |
| SCHEMBL30663133 | 0.73 | CRBN (0.64) | — | |
| SCHEMBL27167653 | 0.73 | DDB1 (0.62) | — | |
| SCHEMBL27168231 | 0.73 | DDB1 (0.62) | — | |
| SCHEMBL30735429 | 0.73 | CRBN (0.64) | — | |
| SCHEMBL26636980 | 0.73 | CRBN (0.64) | — | |
| SCHEMBL28469672 | 0.71 | CHRNB2 (0.39) | KHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112673001-A | Indazole carboxamides as kinase inhibitors | 百时美施贵宝公司 | 2021-04-16 | — | — | CN | disclosed |