SCHEMBL2855642

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2861588	0.89	MAPT (0.39)	CNR2PTGER1CNR1GRM5HPGD
	SCHEMBL2862067	0.76	TTK (0.49)	MEN1KMT2AMAPTJAK3
	SCHEMBL2864808	0.70	MAPT (0.46)	PTGER1GRM5HPGDHTTMEN1
	SCHEMBL121336	0.67	PTGER1 (0.47)	PTGER1HPGD
	SCHEMBL2862660	0.65	PTGER1 (0.36)	CNR2PTGER1HPGDHTTKMT2A
	SCHEMBL31632883	0.64	CSNK2A2 (0.47)	PTGER1HPGDHTTKMT2ASMN1; SMN2
	SCHEMBL2857840	0.64	MAPT (0.41)	PTGER1HPGDHTTMEN1KMT2A
	SCHEMBL2074541	0.64	HPGDS (0.69)	HPGDHTTMEN1KMT2AMAPT
	SCHEMBL2863245	0.63	PTGER1 (0.43)	PTGER1MAPTSMN1; SMN2
	SCHEMBL30940072	0.63	HPGDS (0.58)	CNR2CNR1HPGDHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.