Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 6/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | JAK3 | P52333 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6793430 | 0.90 | HPGDS (0.83) | HPGDSHPGDHTTNPC1RAB9A | |
| SCHEMBL7485708 | 0.82 | HPGDS (0.71) | HPGDSHPGDHTTNPC1RAB9A | |
| SCHEMBL8439895 | 0.82 | HPGDS (0.78) | HPGDSHPGDHTTNPC1RAB9A | |
| SCHEMBL158020 | 0.82 | HPGDS (1.00) | HPGDSHPGDHTTNPC1RAB9A | |
| SCHEMBL28807604 | 0.81 | HPGDS (0.65) | HPGDSHPGDHTTNPC1RAB9A | |
| SCHEMBL11306574 | 0.81 | HPGDS (0.69) | HPGDSHPGDHTTNPC1RAB9A | |
| SCHEMBL5591866 | 0.81 | HPGDS (0.69) | HPGDSHPGDHTTNPC1RAB9A | |
| SCHEMBL6326690 | 0.81 | HPGD (1.00) | HPGDSHPGDHTTNPC1RAB9A | |
| SCHEMBL2760408 | 0.81 | HPGDS (0.69) | HPGDSHPGDHTTNPC1RAB9A | |
| SCHEMBL4420563 | 0.81 | HPGDS (0.69) | HPGDSHPGDHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022148752-A9 | PHOTOCHROMIC DYES AND POLYMERIC MATRIX FOR AN EFFICIENT DIMMING FILM | Sony Group Corporation (JP) | 2023-08-03 | — | — | WO | disclosed |
| WO-2022148752-A2 | PHOTOCHROMIC DYES AND POLYMERIC MATRIX FOR AN EFFICIENT DIMMING FILM | Sony Group Corporation (JP) | 2022-07-14 | — | — | WO | disclosed |
| CN-106432176-A | Synthesis method of thiamethoxam ibuprofen drug intermediate 2-(p-fluorobenzoyl) thiophene | 厦门安普顿信息科技有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-106432176-A | Synthesis method of thiamethoxam ibuprofen drug intermediate 2-(p-fluorobenzoyl) thiophene | 厦门安普顿信息科技有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-105503819-A | Synthesis method of suprofen drug intermediate 2-(p-fluorobenzoyl)thiophene | CHENGDU DONGDIAN AIER TECH CO LTD | 2016-04-20 | — | — | CN | disclosed |
| CN-105503819-A | Synthesis method of suprofen drug intermediate 2-(p-fluorobenzoyl)thiophene | CHENGDU DONGDIAN AIER TECH CO LTD | 2016-04-20 | — | — | CN | disclosed |
| US-8779168-B2 | Lactone compounds and materials made therefrom | TRANSITIONS OPTICAL, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| CN-103554130-A | 2-(4-substituted benzoyl)-4,6-dibromo thiophene bithiophene and preparation method and application thereof | UNIV SOUTH CHINA TECH | 2014-02-05 | — | — | CN | disclosed |
| US-20120157677-A1 | LACTONE COMPOUNDS AND MATERIALS MADE THEREFROM | TRANSITIONS OPTICAL INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-7863444-B2 | 4-aminopyrrolopyrimidines as kinase inhibitors | ABBOTT LABORATORIES (US) | 2011-01-04 | — | — | US | disclosed |
| WO-1999034800-A1 | USE OF PHENYLTHIENYLMETHYLENE PIPERIDINE DERIVATIVE IN THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF MOVEMENT DISORDERS | AKZO NOBEL N.V. (NL) | 1999-07-15 | — | — | WO | disclosed |
| WO-1998021206-A1 | PIPERIDINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 1998-05-22 | — | — | WO | disclosed |
| WO-1998005635-A1 | HYDROXAMIC AND CARBOXYLIC ACID DERIVATIVES HAVING MMP AND TNF INHIBITORY ACTIVITY | DARWIN DISCOVERY LIMITED (GB) | 1998-02-12 | — | — | WO | disclosed |
| US-5516783-A | PLATELET ACTIVATING FACTOR | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-05-14 | — | — | US | disclosed |
| US-5420224-A | Films and fibers with benzoxazole groups | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1995-05-30 | — | — | US | disclosed |
| EP-0635018-A1 | 4-(1H-2-METHYLIMIDAZO 4,5-c]PYRIDINYLMETHYL)PHENYLSULPHONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993016075-A1 | 4-(1H-2-METHYLIMIDAZO[4,5-c]PYRIDINYLMETHYL)PHENYLSULPHONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-08-19 | — | — | WO | disclosed |
| US-4064132-A | ANTIINFLAMMATORY AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 1977-12-20 | — | — | US | disclosed |
| US-4060528-A | ANTIINFLAMMATORY | JANSSEN PHARMACEUTICA N.V. (BE) | 1977-11-29 | — | — | US | disclosed |
| US-4035376-A | ESTERS, AMIDES, HYDROXAMIC ACIDS, ANTIINFLAMMATORY | JANSSEN PHARMACEUTICA N.V. (BE) | 1977-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157677-A1 | LACTONE COMPOUNDS AND MATERIALS MADE THEREFROM | LSS, DCXR, NISCH | HPGDS 38/4885HPGD 19/4885HTT 1265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.