SCHEMBL28556830

SCHEMBL28556830

CNc1ccc(C(=O)O)cc1.CP

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
TSHR P16473 2/20 0.55
TP53 P04637 1/20 0.55
SRD5A2 P31213 3/20 0.50
CSNK2A2 P19784 1/20 0.47
CSNK2B P67870 1/20 0.47
CSNK2A1 P68400 1/20 0.47
CSNK2A3 Q8NEV1 1/20 0.47
EPHX2 P34913 1/20 0.47
NR1H4 Q96RI1 1/20 0.47
HCAR3 P49019 1/20 0.47
KDM4E B2RXH2 1/20 0.47
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
CA12 O43570 1/20 0.46
CA3 P07451 1/20 0.46
TYR P14679 1/20 0.46
DRD1 P21728 1/20 0.46
CA4 P22748 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL98312 0.95 TSHR (0.60) ALDH1A1SMN1; SMN2TSHRTP53SRD5A2
SCHEMBL9177111 0.93 TSHR (0.57) ALDH1A1SMN1; SMN2TSHRTP53SRD5A2
Methyl Alcohol SCHEMBL27778102 0.93 TSHR (0.57) ALDH1A1SMN1; SMN2TSHRTP53SRD5A2
Hydrochloric Acid SCHEMBL7347939 0.93 TSHR (0.57) ALDH1A1SMN1; SMN2TSHRTP53SRD5A2
Ethylene Glycol SCHEMBL7042192 0.87 TP53 (0.50) ALDH1A1SMN1; SMN2TSHRTP53SRD5A2
Oxirane SCHEMBL27918303 0.85 TP53 (0.48) ALDH1A1SMN1; SMN2TSHRTP53SRD5A2
Trifluoroacetic Acid SCHEMBL21177989 0.84 EPHX2 (0.46) ALDH1A1SMN1; SMN2TSHRTP53SRD5A2
Acedoben SCHEMBL8346780 0.84 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2TSHRTP53EPHX2
SCHEMBL11747257 0.82 HCAR3 (0.49) ALDH1A1SMN1; SMN2TSHRTP53CSNK2A2
Tetrylammonium SCHEMBL11746115 0.82 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2TSHRTP53SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107406469-B For extracting C from aqueous streams1To C4Quaternary arylcarboxylate salt compositions of carboxylic acids 伊士曼化工公司 2021-04-30 CN disclosed