Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28557417 | 1.00 | MDM4 (0.45) | MDM4TP53CASP3PTPN1KMT2A | |
| SCHEMBL15452758 | 0.91 | MDM4 (0.47) | MDM4TP53CASP3PTPN1KMT2A | |
| SCHEMBL8123186 | 0.91 | MDM4 (0.47) | MDM4TP53CASP3PTPN1KMT2A | |
| SCHEMBL29480487 | 0.89 | CTSK (0.51) | MDM4TP53PTPN1 | |
| SCHEMBL12677569 | 0.89 | MDM4 (0.49) | MDM4TP53CASP3KMT2A | |
| SCHEMBL30562127 | 0.88 | MDM4 (0.53) | MDM4TP53CASP3 | |
| SCHEMBL1414120 | 0.86 | KMT2A (0.49) | MDM4TP53CASP3PTPN1KMT2A | |
| SCHEMBL1414123 | 0.86 | KMT2A (0.49) | MDM4TP53CASP3PTPN1KMT2A | |
| SCHEMBL29598621 | 0.86 | MDM2 (0.45) | MDM4TP53CASP3KMT2A | |
| SCHEMBL17446658 | 0.85 | MDM4 (0.46) | MDM4TP53CASP3PTPN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112851536-B | Method for constructing amide bond by clicking pyrimidine condensing agent and application of method in amide and polypeptide synthesis | 兰州大学 | 2022-02-25 | — | — | CN | disclosed |
| CN-112851536-A | Method for constructing amide bond by clicking pyrimidine condensing agent and application of method in amide and polypeptide synthesis | 兰州大学 | 2021-05-28 | — | — | CN | disclosed |