SCHEMBL29480487

SCHEMBL29480487

C[C@H](NC(=O)[C@H](COC(C)(C)C)NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OCc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CTSK P43235 2/20 0.51
▸ CTSL P07711 1/20 0.51
▸ CTSS P25774 1/20 0.51
▸ PTPN1 P18031 4/20 0.46
▸ HDAC1 Q13547 1/20 0.46
▸ HDAC2 Q92769 1/20 0.46
▸ TNF P01375 1/20 0.45
▸ MDM4 O15151 1/20 0.44
▸ TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29594352 0.90 HDAC1 (0.51) CTSKCTSLCTSSHDAC1HDAC2
SCHEMBL28557417 0.89 MDM4 (0.45) PTPN1MDM4TP53
SCHEMBL28557416 0.89 MDM4 (0.45) PTPN1MDM4TP53
SCHEMBL29480470 0.87 CTSK (0.57) CTSKCTSLCTSSPTPN1
SCHEMBL17446653 0.87 PTPN1 (0.48) PTPN1HDAC1HDAC2TNFMDM4
SCHEMBL30562127 0.85 MDM4 (0.53) TNFMDM4TP53
SCHEMBL23811018 0.85 KMT2A (0.52) CTSKCTSLCTSSHDAC1HDAC2
SCHEMBL17446655 0.84 HDAC1 (0.50) CTSKCTSLPTPN1HDAC1HDAC2
SCHEMBL30645058 0.83 PTPN1 (0.47) CTSKCTSLPTPN1MDM4TP53
SCHEMBL119575 0.83 MDM4 (0.56) TNFMDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12528834-B2 Method for producing peptide compound NISSAN CHEMICAL CORPORATION (JP) 2026-01-20 — — US disclosed
US-20220372069-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NISSAN CHEMICAL CORPORATION (JP) 2022-11-24 — — US disclosed
EP-4036103-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND Nissan Chemical Corporation (JP) 2022-08-03 — — EP disclosed
CN-114401978-A Method for producing peptide compound 日产化学株式会社 2022-04-26 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528834-B2 Method for producing peptide compound VIP, IAPP, NPPA CTSK 906/4885CTSL 139/4885CTSS 780/4885
US-20220372069-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND VIP, NPPA, NGLY1 CTSK 966/4885CTSL 325/4885CTSS 1134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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