Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030672 | 0.94 | KDM1A (0.59) | KDM1AALDH1A1MEN1KMT2AMAPT | |
| Diphenylamine SCHEMBL11871615 | 0.87 | HSD17B10 (0.60) | KDM1AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10571080 | 0.85 | KDM1A (0.53) | KDM1AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9649012 | 0.85 | ALDH1A1 (0.53) | KDM1AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL29595268 | 0.81 | MAPT (0.62) | KDM1AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL16890463 | 0.81 | MAPT (0.62) | KDM1AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9480018 | 0.80 | ALDH1A1 (0.62) | KDM1AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL2035896 | 0.80 | ALDH1A1 (0.62) | KDM1AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL24400123 | 0.79 | MAPT (0.60) | KDM1AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11732026 | 0.79 | ALDH1A1 (0.54) | KDM1AALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108976107-B | 3-aryl-4-alkoxybenzylamine derivative and preparation method and application thereof | 南方医科大学 | 2021-03-23 | — | — | CN | claimed |
| CN-108976107-B | 3-aryl-4-alkoxybenzylamine derivative and preparation method and application thereof | 南方医科大学 | 2021-03-23 | — | — | CN | disclosed |