SCHEMBL3030672

SCHEMBL3030672

CN(C)c1cccc(Nc2cccc(N(C)C)c2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.59
ALDH1A1 P00352 4/20 0.52
TSHR P16473 1/20 0.52
MAPT P10636 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
AR P10275 1/20 0.48
EGFR P00533 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
GAA P10253 1/20 0.46
ALOX15 P16050 1/20 0.46
MAPK1 P28482 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
BCHE P06276 1/20 0.45
ACHE P22303 1/20 0.45
APP P05067 1/20 0.44
ACP1 P24666 2/20 0.43
JAK2 O60674 1/20 0.43
JAK1 P23458 1/20 0.43
TYK2 P29597 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28557487 0.94 KDM1A (0.63) KDM1AALDH1A1TSHRMAPTMEN1
SCHEMBL9649012 0.87 ALDH1A1 (0.53) KDM1AALDH1A1TSHRMAPTMEN1
SCHEMBL10571080 0.87 KDM1A (0.53) KDM1AALDH1A1TSHRMAPTMEN1
SCHEMBL1268756 0.84 ALDH1A1 (0.50) KDM1AALDH1A1TSHRMAPTMEN1
SCHEMBL31726567 0.84 ALDH1A1 (0.50) KDM1AALDH1A1TSHRMAPTMEN1
SCHEMBL27085702 0.84 KDM1A (0.47) KDM1AALDH1A1TSHRMAPTMEN1
SCHEMBL599074 0.82 ALDH1A1 (0.54) KDM1AALDH1A1TSHRMAPTMEN1
SCHEMBL10089591 0.82 ALDH1A1 (0.48) KDM1AALDH1A1TSHRMAPTMEN1
SCHEMBL11469366 0.82 ALDH1A1 (0.48) KDM1AALDH1A1TSHRMAPTMEN1
Hydrochloric Acid SCHEMBL11291701 0.82 ALDH1A1 (0.48) KDM1AALDH1A1TSHRMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9067900-B2 Diaminophenothiazine compounds, a method for preparing same and uses thereof PHARMA HYDRO DEVELOPMENT—P.H.D. (FR) 2015-06-30 US disclosed
US-9067900-B2 Diaminophenothiazine compounds, a method for preparing same and uses thereof PHARMA HYDRO DEVELOPMENT—P.H.D. (FR) 2015-06-30 US disclosed
US-9067900-B2 Diaminophenothiazine compounds, a method for preparing same and uses thereof PHARMA HYDRO DEVELOPMENT—P.H.D. (FR) 2015-06-30 US disclosed
EP-2185531-B1 Diaminophenothiazine compounds, a method for preparing same and uses thereof PHARMA HYDRO DEV P H D (FR) 2012-07-25 EP disclosed
EP-2185531-B1 Diaminophenothiazine compounds, a method for preparing same and uses thereof PHARMA HYDRO DEV P H D (FR) 2012-07-25 EP disclosed
US-20100204215-A1 NOVEL DIAMINOPHENOTHIAZINE COMPOUNDS, A METHOD FOR PREPARING SAME AND USES THEREOF PHARMA HYDRO DEVELOPMENT - P.H.D. (FR) 2010-08-12 US disclosed
US-20100204215-A1 NOVEL DIAMINOPHENOTHIAZINE COMPOUNDS, A METHOD FOR PREPARING SAME AND USES THEREOF PHARMA HYDRO DEVELOPMENT - P.H.D. (FR) 2010-08-12 US disclosed
US-20100204215-A1 NOVEL DIAMINOPHENOTHIAZINE COMPOUNDS, A METHOD FOR PREPARING SAME AND USES THEREOF PHARMA HYDRO DEVELOPMENT - P.H.D. (FR) 2010-08-12 US disclosed
EP-2185531-A2 NOVEL DIAMINOPHENOTHIAZINE COMPOUNDS, A METHOD FOR PREPARING SAME AND USES THEREOF Pharma Hydro Development - P.H.D. (FR) 2010-05-19 EP disclosed
US-7659416-B2 Monomolecular conductive complex, conductive self-assembled film and assembly of electrode composed of metal and semiconductor making use of the same TOKYO INSTITUTE OF TECHNOLOGY (JP) 2010-02-09 US disclosed
WO-2009044054-A2 NOVEL DIAMINOPHENOTHIAZINE COMPOUNDS, A METHOD FOR PREPARING SAME AND USES THEREOF PHARMA HYDRO DEVELOPMENT - P.H.D. (FR) 2009-04-09 WO disclosed
WO-2009044054-A2 NOVEL DIAMINOPHENOTHIAZINE COMPOUNDS, A METHOD FOR PREPARING SAME AND USES THEREOF PHARMA HYDRO DEVELOPMENT - P.H.D. (FR) 2009-04-09 WO disclosed
US-20090036698-A1 Monomolecular Conductive Complex, Conductive Self-Assembled Film and Assembly of Electrode Composed of Metal and Semiconductor Making Use of the Same TOKYO INSTITUTE OF TECHNOLOGY 2009-02-05 US disclosed
EP-1862453-A1 MONOMOLECULAR CONDUCTIVE COMPLEX, CONDUCTIVE SELF-ASSEMBLED FILM AND ASSEMBLY OF ELECTRODE COMPOSED OF METAL AND SEMICONDUCTOR MAKING USE OF THE SAME Tokyo Institute of Technology (JP) 2007-12-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036698-A1 Monomolecular Conductive Complex, Conductive Self-Assembled Film and Assembly of Electrode Composed of Metal and Semiconductor Making Use of the Same CNTN1, GAP43, AP3M1 KDM1A 3181/4885ALDH1A1 3087/4885TSHR 4396/4885
US-20100204215-A1 NOVEL DIAMINOPHENOTHIAZINE COMPOUNDS, A METHOD FOR PREPARING SAME AND USES THEREOF AOC1, DDT, DDC KDM1A 3081/4885ALDH1A1 135/4885TSHR 4263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.