⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL357469 | 0.79 | CES2 (0.43) | — | |
| SCHEMBL8384 | 0.78 | TSHR (0.35) | — | |
| SCHEMBL7705802 | 0.77 | CES2 (0.36) | — | |
| SCHEMBL29251289 | 0.77 | GRM5 (0.52) | — | |
| SCHEMBL11389327 | 0.75 | TTR (0.44) | — | |
| SCHEMBL2045858 | 0.75 | CES2 (0.34) | — | |
| SCHEMBL97028 | 0.75 | CYP3A4 (0.40) | — | |
| SCHEMBL9671253 | 0.75 | CES2 (0.34) | — | |
| Charcoal, Activated SCHEMBL31286314 | 0.74 | GRM5 (0.50) | — | |
| SCHEMBL4351361 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2122 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4399212-A1 | SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2024-07-17 | — | — | EP | claimed |
| CN-118159542-A | Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents | 拜耳公司 | 2024-06-07 | — | — | CN | claimed |
| CN-116063666-B | Multifunctional polyester material and preparation method and application thereof | 四川大学 | 2024-04-19 | — | — | CN | claimed |
| CN-117486753-A | Fluorine-containing benzoyl diethylamine compound with mosquito repellent effect, method and application thereof in mosquito repellent | 天津科技大学 | 2024-02-02 | — | — | CN | claimed |
| US-20240033318-A1 | PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION | OHIO STATE INNOVATION FOUNDATION | 2024-02-01 | — | — | US | claimed |
| CN-109563135-B | Alpha (V) beta (6) integrin binding peptides and methods of use thereof | 加利福尼亚大学董事会 | 2024-01-23 | — | — | CN | claimed |
| WO-2023214052-A1 | METHOD FOR PRODUCING POLYETHERKETONEKETONE | ARKEMA FRANCE (FR) | 2023-11-09 | — | — | WO | claimed |
| US-11739062-B2 | Methods for 1,4-diazo N-heterocycle synthesis | PURDUE RESEARCH FOUNDATION (US) | 2023-08-29 | — | — | US | claimed |
| CN-116063666-A | Multifunctional polyester material and preparation method and application thereof | 四川大学 | 2023-05-05 | — | — | CN | claimed |
| WO-2023036707-A1 | SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-03-16 | — | — | WO | claimed |
| EP-0041711-B1 | 6-CHLORO- OR 6-BROMO-1,2-DIHYDRO-3H-PYRROLO(1,2-A)-PYRROLE-1-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF, PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYNTEX (U.S.A.) INC. (US) | 1985-04-17 | — | — | EP | claimed |
| US-4362879-A | Isothioureido isoindolediones and use as plant growth regulators | GULF OIL CORPORATION (US) | 1982-12-07 | — | — | US | claimed |
| US-4334070-A | NEUROLEPTIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1982-06-08 | — | — | US | claimed |
| US-4292071-A | Isothioureido isoindolediones and use as plant growth regulators | GULF OIL CORPORATION (US) | 1981-09-29 | — | — | US | claimed |
| US-4282222-A | 3-Piperidino or apiperazino-1-phenyl or 1-substituted phenyl isoquinoline and antidepressant compositions thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-08-04 | — | — | US | claimed |
| US-4207325-A | DIURETIC, SALURETIC, ANTIHYPERTENSIVE AND ANTITHROMBOTIC PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-06-10 | — | — | US | claimed |
| US-4113872-A | DIURETICS, SALURETICS, ANTIHYPERTENSIVE, ANTITHROMBOTIC AGENTS | BAKER AKTIENGESELLSHAFT (DE) | 1978-09-12 | — | — | US | claimed |
| US-4112109-A | DIURETIC, SALURETIC, ANTIHYPERTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-05 | — | — | US | claimed |
| US-4099011-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-04 | — | — | US | claimed |
| US-4069334-A | DIURETICS, HYPOTENSIVES | BAYER AKTIENGESELLSCHAFT (DT) | 1978-01-17 | — | — | US | claimed |