SCHEMBL8384

SCHEMBL8384

O=[C]c1ccccc1[C]=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
CA2 P00918 3/20 0.32
CA1 P00915 2/20 0.32
CYP3A4 P08684 2/20 0.32
CA12 O43570 2/20 0.32
CA9 Q16790 2/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA13 Q8N1Q1 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
MEN1 O00255 4/20 0.32
KMT2A Q03164 4/20 0.32
CDC25B P30305 1/20 0.32
APP P05067 1/20 0.32
CYP2A6 P11509 1/20 0.31
ALOX12 P18054 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3940375 0.85
SCHEMBL10582118 0.85 HDAC8 (0.30)
SCHEMBL98562 0.85 TSHR (0.50) TSHRCA2CA1CYP3A4MEN1
SCHEMBL19887 0.85
SCHEMBL6281274 0.83 MEN1 (0.40) TSHRCA2CA1CA9CA7
SCHEMBL11682735 0.83
SCHEMBL837075 0.79
SCHEMBL49876 0.78
SCHEMBL25504 0.78
SCHEMBL671168 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 31052 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344347-A Benzodioxole compound with anti-tumor activity and preparation method and application thereof 江苏海洋大学 2024-07-16 CN claimed
CN-118287266-A Low-temperature floatation method of spodumene mineral 中国恩菲工程技术有限公司 2024-07-05 CN claimed
CN-114430778-B Increasing the yield of long sequences in template-free enzymatic synthesis of polynucleotides DNA斯克瑞普特公司 2024-07-05 CN claimed
CN-116059355-B Multifunctional nano diagnosis and treatment agent and preparation method and application thereof 福州大学 2024-07-02 CN claimed
CN-115215910-B Chitosan oligosaccharide synthesis method with controllable polymerization degree 山东京博农化科技股份有限公司 2024-06-18 CN claimed
CN-113321600-B Process for preparing chiral biaryl-substituted 4-amino-butanoic acid and derivatives thereof 四川科伦药物研究院有限公司 2024-06-14 CN claimed
WO-2024120505-A1 FUSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, INTERMEDIATES THEREOF, AND USE THEREOF 上海枢境生物科技有限公司 2024-06-13 WO claimed
US-20240190809-A1 THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS AWAKN LS EUROPE HOLDINGS LIMITED (IE) 2024-06-13 US claimed
CN-118165067-A Preparation method of Frag A and intermediate thereof 北京海步医药科技有限公司 2024-06-11 CN claimed
CN-118144379-A Industrial washable reflective material and preparation method thereof 安徽硕明安全科技有限公司 2024-06-07 CN claimed
US-3991108-A PRODUCTION OF ACYL AND CARBAMOYL FLUORIDES AND THEIR CORRESPONDING ISOCYANATES JORDAN ROBERT KENNETH 1976-11-09 US claimed
US-3984417-A Method of producing active amino acid esters AJINOMOTO CO., INC. (JA) 1976-10-05 US claimed
US-3980665-A Optically active salt of protected D-penicillamine and L-lysine DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1976-09-14 US claimed
US-3963697-A Labelled cardiotonic glycosides for use in radioimmunoassay CURTIS NUCLEAR CORPORATION (US) 1976-06-15 US claimed
US-3954783-A Resolution process and salt of protected D-penicillamine and L-pseudonorephedrine DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1976-05-04 US claimed
US-3953437-A Process of preparing cephalosporanic acid ester derivatives YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1976-04-27 US claimed
US-3948882-A ANTIBIOTIC ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) 1976-04-06 US claimed
US-3935198-A BY HEATING THE PENICILLIN SULFOXIDE YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1976-01-27 US claimed
US-3933783-A Formation of peptide bonds in the presence of isonitriles AJINOMOTO CO., INC. (JA) 1976-01-20 US claimed
US-3933736-A HOMO- AND CO-POLYMERS OF ETHYLENE, PROPYLENE, BUTENE-1, PENTENE-1, AND 4-METHYLPENTENE-1 WITH ETHYL ACRYLATE OR VINYL ACETATE UBE INDUSTRIES, LTD. (JA) 1976-01-20 US claimed