SCHEMBL28558102

SCHEMBL28558102

CCCOC(=O)C(C)(CCC)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN1A P35498 3/20 0.52
SCN2A Q99250 3/20 0.52
SCN3A Q9NY46 3/20 0.52
LMNA P02545 3/20 0.52
CYP3A4 P08684 3/20 0.52
CYP2D6 P10635 3/20 0.52
CYP1A2 P05177 2/20 0.52
CYP2C9 P11712 2/20 0.52
CYP2C19 P33261 2/20 0.52
TSHR P16473 1/20 0.52
NFKB1 P19838 1/20 0.52
MTOR P42345 1/20 0.52
RAB9A P51151 1/20 0.52
SIGMAR1 Q99720 1/20 0.52
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
KDM4E B2RXH2 1/20 0.51
NR1I2 O75469 1/20 0.51
CYP1A1 P04798 1/20 0.51
CYP2E1 P05181 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28084453 0.89 PIN1 (0.49) SCN1ASCN2ASCN3ALMNACYP3A4
SCHEMBL29242015 0.89 CHRM2 (0.50) SCN1ASCN2ASCN3ALMNACYP3A4
SCHEMBL10837818 0.88 LMNA (0.51) SCN1ASCN2ASCN3ALMNACYP3A4
SCHEMBL8410004 0.83 KCNN4 (0.55) SCN1ASCN2ASCN3ALMNACYP3A4
SCHEMBL28840742 0.83 CHRM2 (0.46) SCN1ASCN2ASCN3ALMNACYP3A4
SCHEMBL28003870 0.82 SCN1A (0.54) SCN1ASCN2ASCN3ALMNACYP3A4
SCHEMBL10623735 0.81 LMNA (0.53) SCN1ASCN2ASCN3ALMNACYP3A4
SCHEMBL16732185 0.81 LMNA (0.53) SCN1ASCN2ASCN3ALMNACYP3A4
Ammonia Solution, Strong SCHEMBL27636017 0.81 LMNA (0.56) SCN1ASCN2ASCN3ALMNACYP3A4
SCHEMBL5810680 0.80 LMNA (0.51) SCN1ASCN2ASCN3ALMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109678996-B Catalyst component and catalyst system for olefin polymerization, prepolymerized catalyst system and olefin polymerization method 中国石油化工股份有限公司 2021-11-19 CN disclosed
CN-109678998-B Catalyst component and catalyst system for olefin polymerization, prepolymerized catalyst system and olefin polymerization method 中国石油化工股份有限公司 2021-11-19 CN disclosed
CN-109679006-B Catalyst component and catalyst system for olefin polymerization, prepolymerized catalyst system and olefin polymerization method 中国石油化工股份有限公司 2021-08-03 CN disclosed
CN-109679004-B Catalyst component and catalyst system for olefin polymerization, prepolymerized catalyst system and olefin polymerization method 中国石油化工股份有限公司 2021-05-11 CN disclosed