Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL28558145

S.c1ccc2sncc2c1

nearest known ligand 0.38

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 3/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
TDO2 P48775 1/20 0.34
CA12 O43570 2/20 0.33
CA9 Q16790 2/20 0.33
CYP2A6 P11509 1/20 0.33
ALOX12 P18054 1/20 0.33
TRPM5 Q9NZQ8 8/20 0.33
ALDH1A1 P00352 2/20 0.32
HSD17B10 Q99714 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
TRPA1 O75762 2/20 0.32
ADRA2A P08913 1/20 0.31
FBP1 P09467 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
DRD2 P14416 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2877030 0.97
SCHEMBL22858 0.97
SCHEMBL29355782 0.97
SCHEMBL29253629 0.95 SLC6A3 (0.38) SLC6A3SLC6A2SLC6A4TDO2CA12
SCHEMBL28993070 0.95 SLC6A3 (0.38) SLC6A3SLC6A2SLC6A4TDO2CA12
Hydrochloric Acid SCHEMBL10940081 0.95 SLC6A3 (0.38) SLC6A3SLC6A2SLC6A4TDO2CA12
Ammonia Solution, Strong SCHEMBL3715152 0.95 SLC6A3 (0.38) SLC6A3SLC6A2SLC6A4TDO2CA12
SCHEMBL4579663 0.95 SLC6A3 (0.38) SLC6A3SLC6A2SLC6A4TDO2CA12
SCHEMBL27527705 0.95 SLC6A3 (0.38) SLC6A3SLC6A2SLC6A4TDO2CA12
SCHEMBL27470313 0.95 SLC6A3 (0.38) SLC6A3SLC6A2SLC6A4TDO2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117835980-A Tetrahydropyrazolopyridine analog ligand of NLRX1 and application thereof 朗多生物制药股份有限公司 2024-04-05 CN disclosed
CN-109651850-B Method for desulfurization and deashing of coal tar anthracene oil and production of superconducting carbon black 山西永东化工股份有限公司 2021-04-27 CN disclosed