Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TRPM5 | Q9NZQ8 | 8/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2877030 | 0.97 | — | — | |
| SCHEMBL22858 | 0.97 | — | — | |
| SCHEMBL29355782 | 0.97 | — | — | |
| SCHEMBL28993070 | 0.95 | SLC6A3 (0.38) | SLC6A3SLC6A2SLC6A4CYP2A6TDO2 | |
| Hydrochloric Acid SCHEMBL10940081 | 0.95 | SLC6A3 (0.38) | SLC6A3SLC6A2SLC6A4CYP2A6TDO2 | |
| Benzene SCHEMBL27554992 | 0.95 | TDO2 (0.39) | SLC6A3SLC6A2SLC6A4CYP2A6TDO2 | |
| SCHEMBL4579663 | 0.95 | SLC6A3 (0.38) | SLC6A3SLC6A2SLC6A4CYP2A6TDO2 | |
| SCHEMBL29253629 | 0.95 | SLC6A3 (0.38) | SLC6A3SLC6A2SLC6A4CYP2A6TDO2 | |
| Hydrogen Sulfide SCHEMBL28558145 | 0.95 | SLC6A3 (0.38) | SLC6A3SLC6A2SLC6A4CYP2A6TDO2 | |
| Hydrochloric Acid SCHEMBL27262448 | 0.95 | SLC6A3 (0.38) | SLC6A3SLC6A2SLC6A4CYP2A6TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8551981-B2 | Furo[3,2-d]pyrimidine compounds | ABBVIE INC. (US) | 2013-10-08 | — | — | US | disclosed |
| US-20120122846-A1 | FURO[3,2-d]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2012-05-17 | — | — | US | disclosed |
| CN-102209715-A | 4-halo-3 -amino- l, 2 -benzisothiazole compounds as pesticides | SYNGENTA PARTICIPATIONS AG | 2011-10-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122846-A1 | FURO[3,2-d]PYRIMIDINE COMPOUNDS | CDK2, DPYD, CDK3 | SLC6A3 2454/4885SLC6A2 3613/4885SLC6A4 2406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.