Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769314 | 0.83 | HTT (0.66) | HTTMAPTFAAHMGLLMEN1 | |
| SCHEMBL29218271 | 0.81 | KEAP1 (0.50) | HTTMAPTMEN1KMT2ALMNA | |
| SCHEMBL9369399 | 0.81 | HTT (0.68) | HTTMAPTFAAHMGLLMEN1 | |
| SCHEMBL15352874 | 0.79 | HTT (0.66) | HTTMAPTFAAHMGLLMEN1 | |
| SCHEMBL18758370 | 0.79 | HTT (0.66) | HTTMAPTFAAHMGLLMEN1 | |
| SCHEMBL19456984 | 0.79 | HTT (1.00) | HTTMAPTMEN1KMT2ANPC1 | |
| SCHEMBL27887583 | 0.78 | HTT (0.59) | HTTMAPTFAAHMGLLMEN1 | |
| SCHEMBL19457078 | 0.77 | HTT (0.67) | HTTMAPTFAAHMGLLMEN1 | |
| SCHEMBL31274003 | 0.77 | HTT (0.62) | HTTMAPTFAAHMGLLMEN1 | |
| SCHEMBL28354521 | 0.76 | HTT (0.65) | HTTMAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107459521-B | Novel inhibitors of FLT3 kinase and uses thereof | 合肥中科普瑞昇生物医药科技有限公司 | 2021-04-16 | — | — | CN | disclosed |