Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.81 |
| ▸ | CA1 | P00915 | 6/20 | 0.74 |
| ▸ | CA2 | P00918 | 6/20 | 0.74 |
| ▸ | CA12 | O43570 | 1/20 | 0.74 |
| ▸ | CA7 | P43166 | 1/20 | 0.74 |
| ▸ | CA9 | Q16790 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.70 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5380810 | 0.91 | DHFR (0.79) | DHFRCA1CA2CA12CA7 | |
| SCHEMBL10113385 | 0.91 | DHFR (0.79) | DHFRCA1CA2CA12CA7 | |
| SCHEMBL28562281 | 0.90 | DHFR (0.77) | DHFRCA1CA2CA12CA7 | |
| SCHEMBL28555968 | 0.90 | DHFR (0.77) | DHFRCA1CA2CA12CA7 | |
| SCHEMBL28555966 | 0.90 | DHFR (0.77) | DHFRCA1CA2CA12CA7 | |
| SCHEMBL7690389 | 0.89 | DHFR (1.00) | DHFRCA1CA2CA12CA7 | |
| SCHEMBL3168404 | 0.88 | CA1 (0.79) | DHFRCA1CA2CA12CA7 | |
| SCHEMBL10112916 | 0.87 | HSD17B10 (0.76) | DHFRCA1CA2CA12CA7 | |
| SCHEMBL31705348 | 0.86 | DHFR (0.72) | DHFRCA1CA2CA12CA7 | |
| SCHEMBL28564562 | 0.86 | DHFR (0.72) | DHFRCA1CA2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215108-A1 | DUAL G9A/GSK-3ß INHIBITORS | UNIVERSITAT DE BARCELONA (ES) | 2025-10-16 | — | — | WO | claimed |
| WO-2025215108-A1 | DUAL G9A/GSK-3ß INHIBITORS | UNIVERSITAT DE BARCELONA (ES) | 2025-10-16 | — | — | WO | disclosed |
| CN-112812066-B | Synthesis method of dihydropyrimidinone compound | 宜春学院 | 2023-04-25 | — | — | CN | disclosed |
| CN-110437100-B | Preparation method and application of novel ionic salicylaldehyde Schiff base zirconium complex | 山西医科大学 | 2022-03-11 | — | — | CN | disclosed |
| CN-112812066-A | Synthesis method of dihydropyrimidinone compounds | 宜春学院 | 2021-05-18 | — | — | CN | disclosed |