SCHEMBL3168404

SCHEMBL3168404

CCOC(=O)C1=C(C)NC(=S)NC1c1ccc(OC)cc1

nearest known ligand 0.79

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.79
CA2 P00918 4/20 0.79
ALDH1A1 P00352 6/20 0.76
HTT P42858 1/20 0.76
DHFR P00374 2/20 0.75
GUSB P08236 1/20 0.71
CA12 O43570 1/20 0.69
CA7 P43166 1/20 0.69
CA9 Q16790 1/20 0.69
ADORA2B P29275 3/20 0.65
POLB P06746 2/20 0.65
GAA P10253 2/20 0.64
KDM4E B2RXH2 1/20 0.64
LMNA P02545 1/20 0.64
HPGD P15428 1/20 0.64
HSD17B10 Q99714 1/20 0.64
KMT2A Q03164 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7697757 0.89 CA1 (0.74) CA1CA2ALDH1A1HTTDHFR
SCHEMBL28558189 0.88 DHFR (0.81) CA1CA2ALDH1A1HTTDHFR
SCHEMBL10113385 0.87 DHFR (0.79) CA1CA2ALDH1A1HTTDHFR
SCHEMBL5380810 0.87 DHFR (0.79) CA1CA2ALDH1A1DHFRGUSB
SCHEMBL10113348 0.87 DHFR (0.70) CA1CA2ALDH1A1HTTDHFR
SCHEMBL7694042 0.86 ALDH1A1 (1.00) CA1CA2ALDH1A1HTTDHFR
SCHEMBL7695774 0.86 CA1 (0.70) CA1CA2ALDH1A1HTTDHFR
SCHEMBL28555966 0.86 DHFR (0.77) CA1CA2ALDH1A1HTTDHFR
SCHEMBL28555968 0.86 DHFR (0.77) CA1CA2ALDH1A1HTTDHFR
SCHEMBL28562281 0.86 DHFR (0.77) CA1CA2ALDH1A1HTTDHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025215108-A1 DUAL G9A/GSK-3ß INHIBITORS UNIVERSITAT DE BARCELONA (ES) 2025-10-16 WO claimed
CN-116814794-A Biosensor adopting triple amplification strategy and combining fluorescence and electrochemical detection 北京化工大学 2023-09-29 CN claimed
CN-115927294-A U-TaqMan probe, primer, kit, method and application thereof for quantitative detection of coding and non-coding RNA 重庆医科大学国际体外诊断研究院 2023-04-07 CN claimed
WO-2025215108-A1 DUAL G9A/GSK-3ß INHIBITORS UNIVERSITAT DE BARCELONA (ES) 2025-10-16 WO disclosed
US-20240401121-A1 UNIVERSAL HAIRPIN PRIMER SYSTEM FOR QUANTIFICATION OF MICRORNA THE UNIVERSITY OF CHICAGO 2024-12-05 US disclosed
EP-3886555-B1 ROW UNIT FOR AGRICULTURAL IMPLEMENT, AGRICULTURAL IMPLEMENT COMPRISING SUCH ROW UNIT AND METHOD OF SETTING DRILLING DEPTH VAEDERSTAD HOLDING AB (SE) 2024-10-30 EP disclosed
US-12102028-B2 Row unit for agricultural implement, agricultural implement comprising such row unit and method of setting drilling depth VÄDERSTAD HOLDING AB (SE) 2024-10-01 US disclosed
EP-4331557-A1 RADICALLY POLYMERIZABLE COMPOSITION COMPRISING A REDOX INITIATOR SYSTEM BASED ON DIHYDROPYRIDINES Ivoclar Vivadent AG (LI) 2024-03-06 EP disclosed
US-20230402511-A1 SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE FUJI ELECTRIC CO., LTD. (JP) 2023-12-14 US disclosed
CN-116814794-A Biosensor adopting triple amplification strategy and combining fluorescence and electrochemical detection 北京化工大学 2023-09-29 CN disclosed
US-11705780-B2 Generalized jet-effect and generalized generator SOLITON HOLDINGS CORPORATION, DELAWARE CORPORATION (US) 2023-07-18 US disclosed
US-20090324580-A1 Use of Inhibitors of Scavenger Receptor Class Proteins for the Treatment of Infectious Diseases CENIX BIOSCIENCE GMBH (DE) 2009-12-31 US disclosed
US-20090324580-A1 Use of Inhibitors of Scavenger Receptor Class Proteins for the Treatment of Infectious Diseases CENIX BIOSCIENCE GMBH (DE) 2009-12-31 US disclosed
EP-2136626-A1 MANNICH BASE N-OXIDE DRUGS State of Oregon acting by and through the Oregon State Board of Higher Education on behalf of the University of Oregon (US) 2009-12-30 EP disclosed
WO-2008115499-A1 MANNICH BASE N-OXIDE DRUGS STATE OF OREGON ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) 2008-09-25 WO disclosed
US-7160449-B2 Proline chiral columns with broad chiral selectivity VANDERBILT UNIVERSITY (US) 2007-01-09 US disclosed
US-7160449-B2 Proline chiral columns with broad chiral selectivity VANDERBILT UNIVERSITY (US) 2007-01-09 US disclosed
US-7160449-B2 Proline chiral columns with broad chiral selectivity VANDERBILT UNIVERSITY (US) 2007-01-09 US disclosed
US-7141160-B2 Chiral columns with broad chiral selectivity V{dot over (a)}nderbilt University (US) 2006-11-28 US disclosed
US-20050092686-A1 Proline chiral columns with broad chiral selectivity LI, TINGYU 2005-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090324580-A1 Use of Inhibitors of Scavenger Receptor Class Proteins for the Treatment of Infectious Diseases SCARB1, MSR1, HAVCR2 CA1 4872/4885CA2 4782/4885ALDH1A1 511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.