Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | RARB | P10826 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20574599 | 1.00 | MAPT (0.58) | MAPTRARBCES2CES1RAB9A | |
| SCHEMBL13108708 | 0.94 | MAPT (0.63) | MAPTCES2CES1RAB9AL3MBTL1 | |
| SCHEMBL13894709 | 0.88 | L3MBTL1 (0.68) | MAPTRARBRAB9AL3MBTL1KDM4E | |
| SCHEMBL15562010 | 0.88 | RARB (0.68) | MAPTRARBRAB9AL3MBTL1PKM | |
| SCHEMBL9361418 | 0.88 | RARB (0.68) | MAPTRARBRAB9AL3MBTL1PKM | |
| SCHEMBL13448825 | 0.88 | RARB (0.68) | MAPTRARBRAB9AL3MBTL1PKM | |
| SCHEMBL9019628 | 0.88 | RARB (0.68) | MAPTRARBRAB9AL3MBTL1PKM | |
| SCHEMBL4445351 | 0.88 | L3MBTL1 (0.68) | MAPTRARBRAB9AL3MBTL1KDM4E | |
| SCHEMBL21063817 | 0.86 | MAPT (0.80) | MAPTRARBRAB9AL3MBTL1KDM4E | |
| SCHEMBL31146810 | 0.86 | PARP10 (0.65) | MAPTRARBRAB9AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816520-B2 | Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2010-10-19 | — | — | US | disclosed |
| EP-1753747-B1 | 5,6-DIPHENYL-1,2,4-TRIAZINIC DIMERIC DERIVATIVES AND THE USE THEREOF IN THE FORM OF SUN-PROTECTIVE AGENTS | FABRE PIERRE DERMO COSMETIQUE (FR) | 2010-01-13 | — | — | EP | disclosed |
| US-20080267892-A1 | Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267892-A1 | Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair | TYR, H1-0, TELO2 | MAPT 4276/4885RARB 884/4885CES2 932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.