SCHEMBL4445351

SCHEMBL4445351

COCCOCCOc1ccc(C(C)=O)cc1

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.68
GAA P10253 1/20 0.66
MAPT P10636 6/20 0.61
ALDH1A1 P00352 1/20 0.61
LMNA P02545 1/20 0.53
POLB P06746 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
MAOB P27338 6/20 0.51
RARB P10826 1/20 0.51
RAB9A P51151 2/20 0.50
HPGD P15428 1/20 0.50
HRH3 Q9Y5N1 2/20 0.48
MAOA P21397 1/20 0.47
KDM4E B2RXH2 1/20 0.47
RECQL P46063 1/20 0.47
PKM P14618 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13894709 1.00 L3MBTL1 (0.68) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL933535 0.95 L3MBTL1 (0.75) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL8672706 0.93 L3MBTL1 (0.78) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL24935549 0.92 L3MBTL1 (0.67) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL24935614 0.92 L3MBTL1 (0.72) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL30837212 0.90 L3MBTL1 (0.68) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL7186388 0.90 L3MBTL1 (0.62) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL20574599 0.88 MAPT (0.58) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL2855827 0.88 MAPT (0.58) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL834525 0.87 L3MBTL1 (0.88) L3MBTL1GAAMAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3724188-B1 PROGRANULIN MODULATORS AND METHODS OF USING THE SAME ARKUDA THERAPEUTICS (US) 2023-06-07 EP disclosed
WO-2019118528-A1 PROGRANULIN MODULATORS AND METHODS OF USING THE SAME ARKUDA THERAPEUTICS (US) 2019-06-20 WO disclosed
US-8313814-B2 Cellulose acylate film, method of producing the same, cellulose derivative film, optically compensatory film using the same, optically-compensatory film incorporating polarizing plate, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-11-20 US disclosed
US-8313814-B2 Cellulose acylate film, method of producing the same, cellulose derivative film, optically compensatory film using the same, optically-compensatory film incorporating polarizing plate, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-11-20 US disclosed
US-8221855-B2 Cellulose derivative film, optical compensation film, polarizing plate, and liquid crystal device FUJIFILM CORPORATION (JP) 2012-07-17 US disclosed
US-8221855-B2 Cellulose derivative film, optical compensation film, polarizing plate, and liquid crystal device FUJIFILM CORPORATION (JP) 2012-07-17 US disclosed
EP-1899763-B1 LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORP (JP) 2011-11-16 EP disclosed
US-8043714-B2 Transparent thermoplastic film and a method of producing the same FUJIFILM CORPORATION (JP) 2011-10-25 US disclosed
US-7993562-B2 Method of producing a thermoplastic film FUJIFILM CORPORATION (JP) 2011-08-09 US disclosed
US-7981488-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2011-07-19 US disclosed
WO-2007086599-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2007-08-02 WO disclosed
WO-2007086538-A1 RETARDATION PLATE, POLARIZER PLATE, AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPOTATION (JP) 2007-08-02 WO disclosed
WO-2007037539-A9 CELLULOSE DERIVATIVE FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DEVICE FUJIFILM CORP (JP) 2007-05-31 WO disclosed
WO-2007061139-A1 CELLULOSE ACYLATE FILM, METHOD OF PRODUCING THE SAME, CELLULOSE DERIVATIVE FILM, OPTICALLY COMPENSATORY FILM USING THE SAME, OPTICALLY-COMPENSATORY FILM INCORPORATING POLARIZING PLATE, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2007-05-31 WO disclosed
WO-2007037539-A1 CELLULOSE DERIVATIVE FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DEVICE FUJIFILM CORPORATION (JP) 2007-04-05 WO disclosed
WO-2007023990-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJI FILM CORPORATION (JP) 2007-03-01 WO disclosed
US-20040171516-A1 Precursors for ketones and aldehydes GIVAUDAN SA (CH) 2004-09-02 US disclosed
EP-1390337-A1 PRECURSORS FOR KETONES AND ALDEHYDES Givaudan SA (CH) 2004-02-25 EP disclosed
WO-2002096850-A1 PRECURSORS FOR KETONES AND ALDEHYDES GIVAUDAN SA (CH) 2002-12-05 WO disclosed
EP-1262473-A1 Precursors for fragrant ketones and fragrant aldehydes Givaudan SA (CH) 2002-12-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171516-A1 Precursors for ketones and aldehydes PDK3, PDK4, AKR1C4 L3MBTL1 4439/4885GAA 1922/4885MAPT 3633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.