Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 8/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.62 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665376 | 0.88 | OPRK1 (0.60) | OPRD1OPRK1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL4663562 | 0.88 | OPRD1 (0.60) | OPRD1OPRK1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL4667239 | 0.87 | OPRD1 (0.59) | OPRD1OPRK1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL5629292 | 0.87 | OPRK1 (0.59) | OPRD1OPRK1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL4664179 | 0.87 | OPRD1 (0.59) | OPRD1OPRK1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL4665545 | 0.87 | SLC6A2 (0.65) | OPRD1OPRK1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL4663640 | 0.87 | OPRK1 (0.59) | OPRD1OPRK1SLC6A2SLC6A4OPRM1 | |
| Hydrochloric Acid SCHEMBL5439635 | 0.87 | OPRK1 (0.58) | OPRD1OPRK1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL4665488 | 0.87 | OPRK1 (0.58) | OPRD1OPRK1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL4667287 | 0.86 | OPRD1 (0.56) | OPRD1OPRK1SLC6A2SLC6A4OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759538-B | 3- (dimethylaminomethyl) cyclohexan-4-ol derivative, preparation method and pharmaceutical application thereof | 复旦大学 | 2022-01-18 | — | — | CN | disclosed |
| CN-112759538-A | 3- (dimethylaminomethyl) cyclohexan-4-ol derivative, preparation method and pharmaceutical application thereof | 复旦大学 | 2021-05-07 | — | — | CN | disclosed |