Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29538386 | 1.00 | CHRNB2 (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4CYP2C19 | |
| SCHEMBL1278270 | 0.85 | CHRNB2 (0.37) | CHRNB2CHRNB4CHRNA3CHRNA4NAPRT | |
| SCHEMBL30516378 | 0.84 | ERN1 (0.33) | CHRNB2CHRNB4CHRNA3CHRNA4CYP2C19 | |
| SCHEMBL1278426 | 0.83 | CHRNB2 (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4NAPRT | |
| SCHEMBL1156519 | 0.83 | KDM4E (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4NAPRT | |
| SCHEMBL1278456 | 0.83 | CHRNB2 (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4NAPRT | |
| SCHEMBL29141633 | 0.81 | CHRNB2 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4CYP2C19 | |
| SCHEMBL30748192 | 0.81 | CHRNB2 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4CYP2C19 | |
| SCHEMBL30544721 | 0.81 | NAPRT (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4CYP2C19 | |
| SCHEMBL25193028 | 0.81 | CHRNB4 (0.37) | CHRNB2CHRNB4CHRNA3CHRNA4PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812099-B | Compound for treating peptic ulcer and preparation method and application thereof | 珠海赛隆药业股份有限公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-112812099-A | Compound for treating peptic ulcer and preparation method and application thereof | 珠海赛隆药业股份有限公司 | 2021-05-18 | — | — | CN | disclosed |