SCHEMBL28558451

SCHEMBL28558451

C=C(c1ccccc1)c1ccccc1OC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.54
NPC1 O15118 3/20 0.54
ALDH1A1 P00352 3/20 0.47
MAPT P10636 1/20 0.47
KCNK3 O14649 1/20 0.46
KCNK9 Q9NPC2 1/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA12 O43570 1/20 0.46
CA4 P22748 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
HTT P42858 2/20 0.46
CTSD P07339 1/20 0.46
KDM4E B2RXH2 1/20 0.45
LMNA P02545 1/20 0.45
KMT2A Q03164 1/20 0.45
POLB P06746 1/20 0.44
TP53 P04637 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3277622 0.89 CA1 (0.57) RAB9ANPC1KCNK3KCNK9CA1
SCHEMBL27882858 0.85 CTSD (0.45) RAB9ANPC1ALDH1A1MAPTCA1
SCHEMBL28417915 0.84 KCNK3 (0.44) RAB9ANPC1ALDH1A1MAPTKCNK3
SCHEMBL28412833 0.84 NPC1 (0.44) RAB9ANPC1ALDH1A1MAPTKCNK3
SCHEMBL11798261 0.83 HTT (0.44) RAB9ANPC1ALDH1A1MAPTHTT
SCHEMBL11642592 0.83 MEN1 (0.59) RAB9ANPC1ALDH1A1MAPTHTT
SCHEMBL9715772 0.82 RAB9A (0.53) RAB9ANPC1ALDH1A1MAPTKCNK3
SCHEMBL5170335 0.82 TP53 (0.48) RAB9ANPC1ALDH1A1MAPTKCNK3
SCHEMBL21966599 0.81 KMT2A (0.52) ALDH1A1MAPTKDM4ELMNAKMT2A
SCHEMBL13539020 0.81 CA1 (0.52) RAB9ANPC1ALDH1A1KCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112608222-A Method for preparing aldehyde ketone compound by olefin oxidation 三峡大学 2021-04-06 CN disclosed