Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6342635 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TSHRMEN1KMT2AHSD17B10 | |
| SCHEMBL15216528 | 0.80 | NFE2L2 (0.45) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL14992771 | 0.80 | ALDH1A1 (0.42) | ALDH1A1TSHRMEN1KMT2ATDP1 | |
| SCHEMBL14390523 | 0.80 | MEN1 (0.42) | ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL4711162 | 0.80 | ALDH1A1 (0.42) | ALDH1A1TSHRMEN1KMT2ATDP1 | |
| SCHEMBL7921428 | 0.80 | NFE2L2 (0.45) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL14992770 | 0.80 | ALDH1A1 (0.42) | ALDH1A1TSHRMEN1KMT2ATDP1 | |
| SCHEMBL5711300 | 0.77 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL6153742 | 0.77 | NFE2L2 (0.44) | ALDH1A1MEN1KMT2ATDP1MAPT | |
| SCHEMBL7900406 | 0.77 | CA12 (0.37) | ALDH1A1TSHRMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109438288-B | N-nitrone substituted aromatic amide derivative and preparation method thereof | 河南中医药大学 | 2021-05-07 | — | — | CN | disclosed |