Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10997472 | 0.87 | GRM5 (0.53) | GRM5L3MBTL1HTTALDH1A1MAPT | |
| SCHEMBL3888886 | 0.79 | CALM1 (0.50) | ALDH1A1KCNH2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27324689 | 0.78 | GRM5 (0.47) | GRM5L3MBTL1HTTALDH1A1MAPT | |
| SCHEMBL14085329 | 0.78 | CYP1A2 (0.49) | GRM5L3MBTL1HTTALDH1A1MAPT | |
| SCHEMBL967014 | 0.77 | GRM5 (0.46) | GRM5L3MBTL1HTTALDH1A1MAPT | |
| SCHEMBL28546126 | 0.77 | GRM5 (0.54) | GRM5HTTALDH1A1MAPTMEN1 | |
| SCHEMBL17188595 | 0.77 | GRM5 (0.46) | GRM5L3MBTL1HTTALDH1A1MAPT | |
| SCHEMBL2995424 | 0.76 | GRM5 (0.49) | GRM5L3MBTL1HTTALDH1A1MAPT | |
| SCHEMBL30521955 | 0.74 | L3MBTL1 (0.39) | L3MBTL1HTTALDH1A1MAPTKCNH2 | |
| SCHEMBL968474 | 0.74 | GRM5 (0.47) | GRM5L3MBTL1HTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108976248-B | Heterocyclic ring-containing high-valence iodine compound and preparation method and application thereof | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 2021-04-16 | — | — | CN | disclosed |