SCHEMBL28559261

SCHEMBL28559261

FC1(F)CC1c1ccc2ccccc2c1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 7/20 0.46
RCOR1 Q9UKL0 5/20 0.46
KDM4E B2RXH2 1/20 0.46
HTR2C P28335 1/20 0.42
HTR2B P41595 1/20 0.42
SLC6A4 P31645 5/20 0.41
MAOA P21397 2/20 0.41
MAOB P27338 2/20 0.41
SLC6A2 P23975 3/20 0.41
SLC6A3 Q01959 3/20 0.41
CYP2D6 P10635 1/20 0.41
KCNH2 Q12809 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2A6 P11509 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28592336 0.83 KDM1A (0.43) KDM1ARCOR1KDM4EHTR2CHTR2B
SCHEMBL31083268 0.80 KDM1A (0.46) KDM1ARCOR1KDM4EHTR2CHTR2B
SCHEMBL28234117 0.75 POLB (0.49) KDM4ESLC6A4SLC6A2SLC6A3
SCHEMBL28613312 0.74 KDM4E (0.41) KDM1ARCOR1KDM4EHTR2CHTR2B
SCHEMBL1415636 0.73 KDM1A (0.54) KDM1AMAOAMAOB
SCHEMBL5405317 0.70 SLC6A4 (0.59) KDM1AKDM4EHTR2CHTR2BSLC6A4
SCHEMBL27344871 0.70 KDM4E (0.52) KDM4EHTR2CHTR2BSLC6A4SLC6A2
SCHEMBL28559262 0.68 KDM4E (0.46) KDM4EHTR2CHTR2BSLC6A4SLC6A2
SCHEMBL21610765 0.68 MGLL (0.37) KDM1ARCOR1KDM4EMAOAMAOB
SCHEMBL23989466 0.68 HTR2C (0.46) KDM1ARCOR1HTR2CHTR2BSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894556-B Synthesis method of beta-fluoroallylphosphine 南通大学 2025-04-29 CN claimed
CN-115894556-A Synthesis method of beta-fluoroallylphosphine 南通大学 2023-04-04 CN claimed
CN-115584516-A Method for electrochemically inducing defluorination carboxylation reaction of difluorocyclopropane 南京林业大学 2023-01-10 CN claimed
CN-120004780-A Method for synthesizing polysubstituted pyrrole compound by taking difluoro cyclopropane as raw material 平顶山学院 2025-05-16 CN disclosed
CN-115894556-A Synthesis method of beta-fluoroallylphosphine 南通大学 2023-04-04 CN disclosed
CN-115584516-A Method for electrochemically inducing defluorination carboxylation reaction of difluorocyclopropane 南京林业大学 2023-01-10 CN disclosed
CN-112745200-B Method for selective allylation of simple aromatic hydrocarbon with participation of difluorocyclopropane 四川大学 2021-10-22 CN disclosed
CN-112745200-A Method for selective allylation of simple aromatic hydrocarbon with participation of difluorocyclopropane 四川大学 2021-05-04 CN disclosed