Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28560245 | 1.00 | ATM (0.45) | ATMHTTGAAMAOAMAOB | |
| SCHEMBL28960349 | 0.82 | MAOA (0.48) | ATMHTTGAAMAOAMAOB | |
| SCHEMBL28905458 | 0.77 | MEN1 (0.47) | ATMHTTGAAMAOAMAOB | |
| SCHEMBL264821 | 0.74 | ATM (0.71) | ATMHTTGAALMNAL3MBTL1 | |
| SCHEMBL2776027 | 0.74 | ATM (0.71) | ATMHTTGAALMNAL3MBTL1 | |
| SCHEMBL10041972 | 0.74 | ATM (0.71) | ATMHTTGAALMNAL3MBTL1 | |
| SCHEMBL2023916 | 0.74 | MAOA (0.43) | ATMHTTMAOAMAOBEGFR | |
| SCHEMBL7767040 | 0.74 | MAOA (0.54) | HTTMAOAMAOBEGFRMAPK1 | |
| SCHEMBL1702760 | 0.73 | TSHR (0.48) | ATMHTTGAAMAPK1LMNA | |
| SCHEMBL1057122 | 0.73 | ATM (0.52) | ATMHTTGAAMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112645895-B | Isoxazoline derivative with olefin side chain and synthesis method thereof | 浙江工业大学 | 2022-07-26 | — | — | CN | disclosed |
| CN-112645895-A | Isoxazoline derivative with olefin side chain and synthesis method thereof | 浙江工业大学 | 2021-04-13 | — | — | CN | disclosed |