SCHEMBL28560296

SCHEMBL28560296

COc1ccc(CCCC(=O)O)cc1.O=C1c2ccccc2C(=O)N1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
PPARG P37231 1/20 0.55
NR1H3 Q13133 1/20 0.54
ALOX5 P09917 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
PLAAT3 P53816 1/20 0.51
PLAAT5 Q96KN8 1/20 0.51
PLAAT2 Q9NWW9 1/20 0.51
PLAAT4 Q9UL19 1/20 0.51
FFAR1 O14842 2/20 0.51
FFAR4 Q5NUL3 2/20 0.51
KMT2A Q03164 2/20 0.50
HDAC3 O15379 1/20 0.50
MAPK1 P28482 1/20 0.50
ADRA1A P35348 1/20 0.50
HDAC4 P56524 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL503646 0.83 ALOX5 (0.68) ALDH1A1ALOX5CYP1A2CYP3A4CYP2D6
SCHEMBL28557973 0.80 KMT2A (0.55) ALDH1A1NR1H3ALOX5CYP1A2CYP3A4
SCHEMBL1171967 0.79 LTB4R (0.67) ALOX5FFAR1FFAR4
SCHEMBL9663959 0.77 LTB4R (0.69) ALOX5FFAR1FFAR4
SCHEMBL8001859 0.77 LTB4R (0.69) ALOX5FFAR1FFAR4
SCHEMBL709381 0.77 LTB4R (0.69) ALOX5FFAR1FFAR4
SCHEMBL9484086 0.77 LTB4R (0.69) ALOX5FFAR1FFAR4
P-Anisic Acid SCHEMBL28548631 0.76 CA1 (0.62) CYP1A2CYP3A4CYP2C9CYP2C19KMT2A
Valeric Acid SCHEMBL27568555 0.76 CA12 (0.47) ALDH1A1PPARGCYP3A4CYP2D6FFAR1
Anisole SCHEMBL31387002 0.76 FFAR1 (0.74) PLAAT3PLAAT5PLAAT2PLAAT4FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112746289-B Synthesis method of alkyl borate compound 合肥工业大学 2021-11-09 CN disclosed
CN-112746289-A Synthesis method of alkyl borate compound 合肥工业大学 2021-05-04 CN disclosed