Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | FABP1 | P07148 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29963467 | 1.00 | HRH4 (0.38) | HRH4CYP11B2HSD11B1STAT3AR | |
| SCHEMBL28550311 | 0.80 | CHRNB2 (0.37) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL28553558 | 0.79 | ENPP1 (0.36) | HSD11B1ARCA12CA1CA2 | |
| SCHEMBL29963154 | 0.79 | MAPT (0.37) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL28555915 | 0.79 | MAPT (0.37) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL29962679 | 0.79 | PTGS2 (0.38) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL29962873 | 0.79 | PTGS2 (0.38) | STAT3ARFABP1CA12CA1 | |
| SCHEMBL29962859 | 0.79 | ENPP1 (0.36) | HSD11B1ARCA12CA1CA2 | |
| SCHEMBL28541702 | 0.79 | PTGS2 (0.38) | STAT3ARFABP1CA12CA1 | |
| SCHEMBL28546488 | 0.79 | PTGS2 (0.38) | CA12CA1CA2CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112624970-B | Application of 8-bit aryl substituted quinoline nitrogen oxide in plant virus resistance and sterilization | 南开大学 | 2022-10-28 | — | — | CN | claimed |
| CN-112624970-A | Application of 8-bit aryl substituted quinoline nitrogen oxide in plant virus resistance and sterilization | 南开大学 | 2021-04-09 | — | — | CN | claimed |
| CN-112624971-A | 8-aryl substituted quinoline nitrogen oxide synthesized by rhodium-catalyzed carbon-hydrogen bond activation reaction | 南开大学 | 2021-04-09 | — | — | CN | claimed |
| CN-112624970-B | Application of 8-bit aryl substituted quinoline nitrogen oxide in plant virus resistance and sterilization | 南开大学 | 2022-10-28 | — | — | CN | disclosed |
| CN-112624970-A | Application of 8-bit aryl substituted quinoline nitrogen oxide in plant virus resistance and sterilization | 南开大学 | 2021-04-09 | — | — | CN | disclosed |
| CN-112624971-A | 8-aryl substituted quinoline nitrogen oxide synthesized by rhodium-catalyzed carbon-hydrogen bond activation reaction | 南开大学 | 2021-04-09 | — | — | CN | disclosed |