SCHEMBL28560772

SCHEMBL28560772

CCCCCCCCCCCCC(N)(N)[Si](OC)(OC)OC

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 5/20 0.40
FDPS P14324 3/20 0.39
LMNA P02545 1/20 0.37
TSHR P16473 2/20 0.35
THRB P10828 1/20 0.35
DNM1 Q05193 4/20 0.33
SPHK2 Q9NRA0 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
GGPS1 O95749 1/20 0.33
ALDH1A1 P00352 1/20 0.33
EPHX1 P07099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL20561212 0.78 SMPD1 (0.37) SMPD1FDPSLMNATSHRTHRB
Hydrochloric Acid SCHEMBL25305152 0.78 SMPD1 (0.37) SMPD1FDPSLMNATSHRTHRB
Hydrochloric Acid SCHEMBL6389524 0.78 SMPD1 (0.37) SMPD1FDPSLMNATSHRTHRB
SCHEMBL28251609 0.77 TSHR (0.38) SMPD1FDPSLMNATSHRTHRB
SCHEMBL5912017 0.76 SMPD1 (0.40) SMPD1FDPSLMNASPHK2
Hydrochloric Acid SCHEMBL21145541 0.76 SMPD1 (0.36) SMPD1FDPSLMNADNM1SPHK2
Hydrochloric Acid SCHEMBL5560162 0.76 SMPD1 (0.36) SMPD1FDPSLMNADNM1SPHK2
SCHEMBL8845866 0.76 TSHR (0.36) SMPD1FDPSLMNATSHRTHRB
SCHEMBL2927935 0.76 TSHR (0.36) SMPD1FDPSLMNATSHRTHRB
SCHEMBL6239174 0.74 CES2 (0.39) SMPD1FDPSLMNATSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110511672-B Bottom-coating active siloxane composition and preparation method and application thereof 广东普赛达密封粘胶有限公司 2021-05-04 CN disclosed