SCHEMBL6239174

SCHEMBL6239174

CCCCCCCCCCCCCCCCCCCCCC(F)(CCCCCCCCCCC)[Si](OC)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.39
LPAR1 Q92633 1/20 0.39
LPAR3 Q9UBY5 1/20 0.39
SMPD1 P17405 3/20 0.35
FDPS P14324 1/20 0.35
TSHR P16473 2/20 0.35
THRB P10828 1/20 0.35
FAAH O00519 7/20 0.33
CES1 P23141 5/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GGPS1 O95749 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29012028 1.00 CES2 (0.39) CES2LPAR1LPAR3SMPD1FDPS
SCHEMBL3440984 1.00 CES2 (0.39) CES2LPAR1LPAR3SMPD1FDPS
SCHEMBL25414443 0.81 CES2 (0.38) CES2LPAR1LPAR3SMPD1FDPS
SCHEMBL25335915 0.81 CES2 (0.38) CES2LPAR1LPAR3SMPD1FDPS
SCHEMBL28517614 0.81 CES2 (0.38) CES2LPAR1LPAR3SMPD1FDPS
SCHEMBL29213124 0.77 CES2 (0.42) CES2LPAR1LPAR3SMPD1FDPS
SCHEMBL19858478 0.77 CES2 (0.42) CES2LPAR1LPAR3SMPD1FDPS
SCHEMBL28352166 0.77 CES2 (0.42) CES2LPAR1LPAR3SMPD1FDPS
SCHEMBL28251609 0.77 TSHR (0.38) CES2LPAR1LPAR3SMPD1FDPS
SCHEMBL7559627 0.76 CES2 (0.39) CES2LPAR1LPAR3SMPD1FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0947478-B1 Water-repellent solution and method of forming water-repellent film on substrate by using the solution CENTRAL GLASS CO LTD (JP) 2005-07-13 EP disclosed
US-6461670-B2 FLUORINATED POLYSILOXANES CENTRAL GLASS COMPANY, LTD. (JP) 2002-10-08 US disclosed
US-20010019773-A1 Water-repellent solution and method of forming water-repellent film on substrate by using the solution AKAMATSU YOSHINORI (JP) 2001-09-06 US disclosed
US-6235833-B1 PRODUCED BY SUBJECTING A FLUOROALKYL-GROUP CONTAINING SILANE COMPOUND TO A HYDROLYSIS AND A CONDENSATION POLYMERIZATION. WITH THIS, AT LEAST DIMERS AND TRIMERS OF THE SILANE COMPOUND ARE PRODUCED. CENTRAL GLASS COMPANY, LIMITED (JP) 2001-05-22 US disclosed
EP-0947478-A1 Water-repellent solution and method of forming water-repellent film on substrate by using the solution Central Glass Company, Limited (JP) 1999-10-06 EP disclosed